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Complete Remission of Widely Metastatic Human Epidermal Growth Factor Receptor 2-Amplified Pancreatic Adenocarcinoma After Precision Immune and Targeted Therapy With Description of Sequencing and Organoid Correlates.
King DA, Smith AR, Pineda G, Nakano M, Michelini F, Goedegebuure SP, Thyparambil S, Liao WL, McCormick A, Ju J, Cioffi M, Zhang X, Hundal J, Griffith M, Grandori C, Pollastro M, Rosati R, Margossian A, Chatterjee P, Ainge T, Flory M, Ocampo P, Chen LM, Poultsides GA, Baron AD, Chang DT, Herman JM, Gillanders WE, Park H, Hoos WA, Nichols M, Fisher GA, Kuo CJ. King DA, et al. Among authors: zhang x. JCO Precis Oncol. 2023 Apr;7:e2100489. doi: 10.1200/PO.21.00489. JCO Precis Oncol. 2023. PMID: 37079860 Free PMC article. No abstract available.
Identification and translational validation of novel mammaglobin-A CD8 T cell epitopes.
Soysal SD, Muenst S, Kan-Mitchell J, Huarte E, Zhang X, Wilkinson-Ryan I, Fleming T, Tiriveedhi V, Mohanakumar T, Li L, Herndon J, Oertli D, Goedegebuure SP, Gillanders WE. Soysal SD, et al. Among authors: zhang x. Breast Cancer Res Treat. 2014 Oct;147(3):527-37. doi: 10.1007/s10549-014-3129-x. Epub 2014 Sep 12. Breast Cancer Res Treat. 2014. PMID: 25212176 Free PMC article. Clinical Trial.
Personalized cancer vaccines: Targeting the cancer mutanome.
Zhang X, Sharma PK, Peter Goedegebuure S, Gillanders WE. Zhang X, et al. Vaccine. 2017 Feb 15;35(7):1094-1100. doi: 10.1016/j.vaccine.2016.05.073. Epub 2016 Jul 20. Vaccine. 2017. PMID: 27449681 Free PMC article. Review.
Breast Cancer Neoantigens Can Induce CD8+ T-Cell Responses and Antitumor Immunity.
Zhang X, Kim S, Hundal J, Herndon JM, Li S, Petti AA, Soysal SD, Li L, McLellan MD, Hoog J, Primeau T, Myers N, Vickery TL, Sturmoski M, Hagemann IS, Miller CA, Ellis MJ, Mardis ER, Hansen T, Fleming TP, Goedegebuure SP, Gillanders WE. Zhang X, et al. Cancer Immunol Res. 2017 Jul;5(7):516-523. doi: 10.1158/2326-6066.CIR-16-0264. Epub 2017 Jun 15. Cancer Immunol Res. 2017. PMID: 28619968 Free PMC article.
Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles.
Strand MS, Krasnick BA, Pan H, Zhang X, Bi Y, Brooks C, Wetzel C, Sankpal N, Fleming T, Goedegebuure SP, DeNardo DG, Gillanders WE, Hawkins WG, Wickline SA, Fields RC. Strand MS, et al. Among authors: zhang x. Oncotarget. 2019 Jul 30;10(46):4761-4775. doi: 10.18632/oncotarget.27109. eCollection 2019 Jul 30. Oncotarget. 2019. PMID: 31413817 Free PMC article.
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.
Li L, Zhang X, Wang X, Kim SW, Herndon JM, Becker-Hapak MK, Carreno BM, Myers NB, Sturmoski MA, McLellan MD, Miller CA, Johanns TM, Tan BR, Dunn GP, Fleming TP, Hansen TH, Goedegebuure SP, Gillanders WE. Li L, et al. Among authors: zhang x. Genome Med. 2021 Apr 21;13(1):56. doi: 10.1186/s13073-021-00872-4. Genome Med. 2021. PMID: 33879241 Free PMC article.
Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology.
Panni UY, Chen MY, Zhang F, Cullinan DR, Li L, James CA, Zhang X, Rogers S, Alarcon A, Baer JM, Zhang D, Gao F, Miller CA, Gong Q, Lim KH, DeNardo DG, Goedegebuure SP, Gillanders WE, Hawkins WG. Panni UY, et al. Among authors: zhang f, zhang d, zhang x. Cancer Immunol Immunother. 2023 Aug;72(8):2813-2827. doi: 10.1007/s00262-023-03463-x. Epub 2023 May 13. Cancer Immunol Immunother. 2023. PMID: 37179276 Free PMC article.
Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients.
Zhang X, Goedegebuure SP, Chen MY, Mishra R, Zhang F, Yu YY, Singhal K, Li L, Gao F, Myers NB, Vickery T, Hundal J, McLellan MD, Sturmoski MA, Kim SW, Chen I, Davidson JT 4th, Sankpal NV, Myles S, Suresh R, Ma CX, Foluso A, Wang-Gillam A, Davies S, Hagemann IS, Mardis ER, Griffith O, Griffith M, Miller CA, Hansen TH, Fleming TP, Schreiber RD, Gillanders WE. Zhang X, et al. Among authors: zhang f. Genome Med. 2024 Nov 14;16(1):131. doi: 10.1186/s13073-024-01388-3. Genome Med. 2024. PMID: 39538331 Free PMC article. Clinical Trial.
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