Tanday N - Search Results

1

The glucagon receptor antagonist desHis¹Pro⁴Glu⁹-glucagon(Lys¹²PAL) alters alpha-cell turnover and lineage in mice, but does not cause alpha-cell hyperplasia.

Lafferty R, Tanday N, Dubey V, Coulter-Parkhill A, Vishal K, Moffett C, O'Harte F, Flatt PR, Irwin N. Lafferty R, et al. Among authors: tanday n. Mol Cell Endocrinol. 2023 Jun 15;570:111932. doi: 10.1016/j.mce.2023.111932. Epub 2023 Apr 18. Mol Cell Endocrinol. 2023. PMID: 37080378 Free article.

2

Exendin-4(Lys²⁷ PAL)/gastrin/xenin-8-Gln: A novel acylated GLP-1/gastrin/xenin hybrid peptide that improves metabolic status in obese-diabetic (ob/ob) mice.

Hasib A, Ng MT, Tanday N, Craig SL, Gault VA, Flatt PR, Irwin N. Hasib A, et al. Among authors: tanday n. Diabetes Metab Res Rev. 2019 Mar;35(3):e3106. doi: 10.1002/dmrr.3106. Epub 2018 Dec 19. Diabetes Metab Res Rev. 2019. PMID: 30499633

3

Peptide YY (1-36) peptides from phylogenetically ancient fish targeting mammalian neuropeptide Y1 receptors demonstrate potent effects on pancreatic β-cell function, growth and survival.

Lafferty RA, Tanday N, McCloskey A, Bompada P, De Marinis Y, Flatt PR, Irwin N. Lafferty RA, et al. Among authors: tanday n. Diabetes Obes Metab. 2020 Mar;22(3):404-416. doi: 10.1111/dom.13908. Epub 2019 Dec 9. Diabetes Obes Metab. 2020. PMID: 31692207

4

Effects of long-acting GIP, xenin and oxyntomodulin peptide analogues on alpha-cell transdifferentiation in insulin-deficient diabetic Glu^CreERT2;ROSA26-eYFP mice.

Sarnobat D, Moffett RC, Gault VA, Tanday N, Reimann F, Gribble FM, Flatt PR, Irwin N. Sarnobat D, et al. Among authors: tanday n. Peptides. 2020 Mar;125:170205. doi: 10.1016/j.peptides.2019.170205. Epub 2019 Nov 16. Peptides. 2020. PMID: 31738969 Free PMC article.

5

Liraglutide and sitagliptin counter beta- to alpha-cell transdifferentiation in diabetes.

Tanday N, Flatt PR, Irwin N, Moffett RC. Tanday N, et al. J Endocrinol. 2020 Apr;245(1):53-64. doi: 10.1530/JOE-19-0451. J Endocrinol. 2020. PMID: 31977315

6

Development and characterisation of a peptidergic N-and C-terminally stabilised mammalian NPY1R agonist which protects against diabetes induction.

Lafferty RA, Tanday N, Flatt PR, Irwin N. Lafferty RA, et al. Among authors: tanday n. Biochim Biophys Acta Gen Subj. 2020 May;1864(5):129543. doi: 10.1016/j.bbagen.2020.129543. Epub 2020 Jan 30. Biochim Biophys Acta Gen Subj. 2020. PMID: 32007578

7

Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta- to alpha-cell transdifferentiation in mouse models of diabetes and insulin resistance.

Tanday N, Irwin N, Flatt PR, Moffett RC. Tanday N, et al. Biochem Pharmacol. 2020 Jul;177:114009. doi: 10.1016/j.bcp.2020.114009. Epub 2020 Apr 30. Biochem Pharmacol. 2020. PMID: 32360307

8

Enzymatically stable analogue of the gut-derived peptide xenin on beta-cell transdifferentiation in high fat fed and insulin-deficient Ins1^Cre/+ ;Rosa26-eYFP mice.

Tanday N, Moffett RC, Gault VA, Flatt PR, Irwin N. Tanday N, et al. Diabetes Metab Res Rev. 2021 Mar;37(3):e3384. doi: 10.1002/dmrr.3384. Epub 2020 Aug 18. Diabetes Metab Res Rev. 2021. PMID: 32662136

9

Generation and characterisation of C-terminally stabilised PYY molecules with potential in vivo NPYR2 activity.

Lafferty RA, Tanday N, Flatt PR, Irwin N. Lafferty RA, et al. Among authors: tanday n. Metabolism. 2020 Oct;111:154339. doi: 10.1016/j.metabol.2020.154339. Epub 2020 Aug 7. Metabolism. 2020. PMID: 32777442

10

Beneficial actions of a long-acting apelin analogue in diabetes are related to positive effects on islet cell turnover and transdifferentiation.

Tanday N, Irwin N, Moffett RC, Flatt PR, O'Harte FPM. Tanday N, et al. Diabetes Obes Metab. 2020 Dec;22(12):2468-2478. doi: 10.1111/dom.14177. Epub 2020 Sep 21. Diabetes Obes Metab. 2020. PMID: 32844576

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