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Page 1
A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases.
Addante A, Raymond W, Gitlin I, Charbit A, Orain X, Scheffler AW, Kuppe A, Duerr J, Daniltchenko M, Drescher M, Graeber SY, Healy AM, Oscarson S, Fahy JV, Mall MA. Addante A, et al. Among authors: fahy jv. Eur Respir J. 2023 May 25;61(5):2202022. doi: 10.1183/13993003.02022-2022. Print 2023 May. Eur Respir J. 2023. PMID: 37080569 Free PMC article.
Quantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts.
Trivedi AP, Hall C, Goss CW, Lew D, Krings JG, McGregor MC, Samant M, Sieren JP, Li H, Schechtman KB, Schirm J, McEleney S, Peterson S, Moore WC, Bleecker ER, Meyers DA, Israel E, Washko GR, Levy BD, Leader JK, Wenzel SE, Fahy JV, Schiebler ML, Fain SB, Jarjour NN, Mauger DT, Reinhardt JM, Newell JD Jr, Hoffman EA, Castro M, Sheshadri A; NHLBI Severe Asthma Research Program (SARP). Trivedi AP, et al. Among authors: fahy jv. Radiology. 2022 Aug;304(2):450-459. doi: 10.1148/radiol.210363. Epub 2022 Apr 26. Radiology. 2022. PMID: 35471111 Free PMC article.
Multicohort Analysis of Bronchial Epithelial Cell Expression in Healthy Subjects and Patients with Asthma Reveals Four Clinically Distinct Clusters.
Lee I, Ganesan A, Kalesinskas L, Zheng H, Ahn HC, Christenson S, Erzurum SC, Zein J, Bleecker ER, Meyers DA, Castro M, Fahy JV, Israel E, Jarjour NN, Moore W, Wenzel SE, Mauger DT, Levy BD, Woodruff PG, Ortega VE, Khatri P. Lee I, et al. Among authors: fahy jv. Am J Respir Cell Mol Biol. 2024 Dec 19. doi: 10.1165/rcmb.2024-0125OC. Online ahead of print. Am J Respir Cell Mol Biol. 2024. PMID: 39700523
Type 1 Immune Responses Related to Viral Infection Influence Corticosteroid Response in Asthma.
Fahy JV, Jackson ND, Sajuthi SP, Pruesse E, Moore CM, Everman JL, Rios C, Tang M, Gauthier M, Wenzel SE, Bleecker ER, Castro M, Comhair SA, Erzurum SC, Hastie AT, Moore W, Israel E, Levy BD, Denlinger L, Jarjour NN, Johansson MW, Mauger DT, Phillips BR, Sumino K, Woodruff PG, Peters MC, Seibold MA; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3. Fahy JV, et al. Am J Respir Crit Care Med. 2024 Nov 27. doi: 10.1164/rccm.202402-0403OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 39601762
Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts.
Zein JG, Zounemat-Kerman N, Adcock IM, Hu B, Attaway A, Castro M, Dahlén SE, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore W, Peters MC, Sumino K, Townsend E, Woodruff P, Ortega VE, Wenzel SE, Meyers DA, Chung KF, Bleecker ER; Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) Consortium and the the US National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP III). Zein JG, et al. Among authors: fahy jv. Lancet Respir Med. 2024 Nov 22:S2213-2600(24)00250-9. doi: 10.1016/S2213-2600(24)00250-9. Online ahead of print. Lancet Respir Med. 2024. PMID: 39586307
Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations.
Xu W, Hong YS, Hu B, Comhair SAA, Janocha AJ, Zein JG, Chen R, Meyers DA, Mauger DT, Ortega VE, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, Wenzel SE, Gaston B, Liu C, Arking DE, Erzurum SC; National Heart, Lung, and Blood Institute (NHLBI) Severe Asthma Research Program and TOPMed mtDNA Working Group in NHLBI Trans-omics for Precision Medicine (TOPMed) Consortium. Xu W, et al. Among authors: fahy jv. J Allergy Clin Immunol. 2024 Sep 3:S0091-6749(24)00906-0. doi: 10.1016/j.jaci.2024.08.022. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 39237012
Peroxidase-mediated mucin cross-linking drives pathologic mucus gel formation in IL-13-stimulated airway epithelial cells.
Liegeois MA, Braunreuther M, Charbit AR, Raymond WW, Tang M, Woodruff PG, Christenson SA, Castro M, Erzurum SC, Israel E, Jarjour NN, Levy BD, Moore WC, Wenzel SE, Fuller GG, Fahy JV. Liegeois MA, et al. Among authors: fahy jv. JCI Insight. 2024 Jun 18;9(15):e181024. doi: 10.1172/jci.insight.181024. JCI Insight. 2024. PMID: 38889046 Free PMC article.
A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma.
Everman JL, Sajuthi SP, Liegeois MA, Jackson ND, Collet EH, Peters MC, Chioccioli M, Moore CM, Patel BB, Dyjack N, Powell R, Rios C, Montgomery MT, Eng C, Elhawary JR, Mak ACY, Hu D, Huntsman S, Salazar S, Feriani L, Fairbanks-Mahnke A, Zinnen GL, Michel CR, Gomez J, Zhang X, Medina V, Chu HW, Cicuta P, Gordon ED, Zeitlin P, Ortega VE, Reisdorph N, Dunican EM, Tang M, Elicker BM, Henry TS, Bleecker ER, Castro M, Erzurum SC, Israel E, Levy BD, Mauger DT, Meyers DA, Sumino K, Gierada DS, Hastie AT, Moore WC, Denlinger LC, Jarjour NN, Schiebler ML, Wenzel SE, Woodruff PG, Rodriguez-Santana J, Pearson CG, Burchard EG, Fahy JV, Seibold MA. Everman JL, et al. Among authors: fahy jv. Nat Commun. 2024 May 9;15(1):3900. doi: 10.1038/s41467-024-48034-5. Nat Commun. 2024. PMID: 38724552 Free PMC article.
Utility of eosinophil peroxidase as a biomarker of eosinophilic inflammation in asthma.
Tang M, Charbit AR, Johansson MW, Jarjour NN, Denlinger LC, Raymond WW, Peters MC, Dunican EM, Castro M, Sumino K, Erzurum SC, Comhair SA, Moore WC, Levy BD, Israel E, Phipatanakul W, Phillips BR, Mauger DT, Bleecker ER, Wenzel SE, Fajt ML, Woodruff PG, Hastie AT, Fahy JV; National Heart Lung and Blood Institute Severe Asthma Research Program. Tang M, et al. Among authors: fahy jv. J Allergy Clin Immunol. 2024 Sep;154(3):580-591.e6. doi: 10.1016/j.jaci.2024.03.023. Epub 2024 Apr 23. J Allergy Clin Immunol. 2024. PMID: 38663815 Free article.
233 results