Leir SH - Search Results

1

Transcriptomic analysis of lung development in wildtype and CFTR^-/- sheep suggests an early inflammatory signature in the CF distal lung.

Kerschner JL, Paranjapye A, Schacht M, Meckler F, Huang F, Bebek G, Van Wettere AJ, Regouski M, Perisse IV, White KL, Polejaeva IA, Leir SH, Harris A. Kerschner JL, et al. Among authors: leir sh. Funct Integr Genomics. 2023 Apr 22;23(2):135. doi: 10.1007/s10142-023-01050-y. Funct Integr Genomics. 2023. PMID: 37085733 Free PMC article.

2

Mucin glycosylation and sulphation in airway epithelial cells is not influenced by cystic fibrosis transmembrane conductance regulator expression.

Leir SH, Parry S, Palmai-Pallag T, Evans J, Morris HR, Dell A, Harris A. Leir SH, et al. Am J Respir Cell Mol Biol. 2005 May;32(5):453-61. doi: 10.1165/rcmb.2004-0306OC. Epub 2005 Jan 27. Am J Respir Cell Mol Biol. 2005. PMID: 15677769 Free article.

3

Novel regulatory mechanisms for the CFTR gene.

Ott CJ, Blackledge NP, Leir SH, Harris A. Ott CJ, et al. Among authors: leir sh. Biochem Soc Trans. 2009 Aug;37(Pt 4):843-8. doi: 10.1042/BST0370843. Biochem Soc Trans. 2009. PMID: 19614605 Free PMC article. Review.

4

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus.

Ott CJ, Blackledge NP, Kerschner JL, Leir SH, Crawford GE, Cotton CU, Harris A. Ott CJ, et al. Among authors: leir sh. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19934-9. doi: 10.1073/pnas.0900946106. Epub 2009 Nov 6. Proc Natl Acad Sci U S A. 2009. PMID: 19897727 Free PMC article.

5

The characterization of the first anti-mouse Muc6 antibody shows an increased expression of the mucin in pancreatic tissue of Cftr-knockout mice.

Gouyer V, Leir SH, Tetaert D, Liu Y, Gottrand F, Harris A, Desseyn JL. Gouyer V, et al. Among authors: leir sh. Histochem Cell Biol. 2010 May;133(5):517-25. doi: 10.1007/s00418-010-0688-8. Epub 2010 Mar 23. Histochem Cell Biol. 2010. PMID: 20309575

6

MicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene.

Gillen AE, Gosalia N, Leir SH, Harris A. Gillen AE, et al. Among authors: leir sh. Biochem J. 2011 Aug 15;438(1):25-32. doi: 10.1042/BJ20110672. Biochem J. 2011. PMID: 21689072 Free PMC article.

7

MUC6 mucin expression inhibits tumor cell invasion.

Leir SH, Harris A. Leir SH, et al. Exp Cell Res. 2011 Oct 15;317(17):2408-19. doi: 10.1016/j.yexcr.2011.07.021. Epub 2011 Aug 5. Exp Cell Res. 2011. PMID: 21851820

8

Molecular mechanisms controlling CFTR gene expression in the airway.

Zhang Z, Ott CJ, Lewandowska MA, Leir SH, Harris A. Zhang Z, et al. Among authors: leir sh. J Cell Mol Med. 2012 Jun;16(6):1321-30. doi: 10.1111/j.1582-4934.2011.01439.x. J Cell Mol Med. 2012. PMID: 21895967 Free PMC article.

9

Nucleosome occupancy reveals regulatory elements of the CFTR promoter.

Ott CJ, Bischof JM, Unti KM, Gillen AE, Leir SH, Harris A. Ott CJ, et al. Among authors: leir sh. Nucleic Acids Res. 2012 Jan;40(2):625-37. doi: 10.1093/nar/gkr754. Epub 2011 Sep 24. Nucleic Acids Res. 2012. PMID: 21948798 Free PMC article.

10

A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function.

Bischof JM, Ott CJ, Leir SH, Gosalia N, Song L, London D, Furey TS, Cotton CU, Crawford GE, Harris A. Bischof JM, et al. Among authors: leir sh. Thorax. 2012 May;67(5):385-91. doi: 10.1136/thoraxjnl-2011-200880. Epub 2011 Dec 14. Thorax. 2012. PMID: 22169360 Free PMC article.

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