Liessi N - Search Results

1

The combination elexacaftor/tezacaftor/ivacaftor (ETI) modulates the de novo synthethic pathway of ceramides in a genotype-independent manner.

Liessi N, Tomati V, Capurro V, Loberto N, Garcia-Aloy M, Franceschi P, Aureli M, Pedemonte N, Armirotti A. Liessi N, et al. J Cyst Fibros. 2023 Jul;22(4):680-682. doi: 10.1016/j.jcf.2023.04.012. Epub 2023 Apr 21. J Cyst Fibros. 2023. PMID: 37088636

2

CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium.

Braccia C, Christopher JA, Crook OM, Breckels LM, Queiroz RML, Liessi N, Tomati V, Capurro V, Bandiera T, Baldassari S, Pedemonte N, Lilley KS, Armirotti A. Braccia C, et al. Among authors: liessi n. Cells. 2022 Jun 16;11(12):1938. doi: 10.3390/cells11121938. Cells. 2022. PMID: 35741067 Free PMC article.

3

Distinctive lipid signatures of bronchial epithelial cells associated with cystic fibrosis drugs, including Trikafta.

Liessi N, Pesce E, Braccia C, Bertozzi SM, Giraudo A, Bandiera T, Pedemonte N, Armirotti A. Liessi N, et al. JCI Insight. 2020 Aug 20;5(16):e138722. doi: 10.1172/jci.insight.138722. JCI Insight. 2020. PMID: 32673287 Free PMC article.

4

Proteomics and Metabolomics for Cystic Fibrosis Research.

Liessi N, Pedemonte N, Armirotti A, Braccia C. Liessi N, et al. Int J Mol Sci. 2020 Jul 30;21(15):5439. doi: 10.3390/ijms21155439. Int J Mol Sci. 2020. PMID: 32751630 Free PMC article. Review.

5

New Insights into the Binding Features of F508del CFTR Potentiators: A Molecular Docking, Pharmacophore Mapping and QSAR Analysis Approach.

Righetti G, Casale M, Tonelli M, Liessi N, Fossa P, Pedemonte N, Millo E, Cichero E. Righetti G, et al. Among authors: liessi n. Pharmaceuticals (Basel). 2020 Dec 4;13(12):445. doi: 10.3390/ph13120445. Pharmaceuticals (Basel). 2020. PMID: 33291847 Free PMC article.

6

Quantification of Changes in Protein Expression Using SWATH Proteomics.

Braccia C, Liessi N, Armirotti A. Braccia C, et al. Among authors: liessi n. Methods Mol Biol. 2021;2361:75-94. doi: 10.1007/978-1-0716-1641-3_5. Methods Mol Biol. 2021. PMID: 34236656

7

β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration.

Lunghi G, Carsana EV, Loberto N, Cioccarelli L, Prioni S, Mauri L, Bassi R, Duga S, Straniero L, Asselta R, Soldà G, Di Fonzo A, Frattini E, Magni M, Liessi N, Armirotti A, Ferrari E, Samarani M, Aureli M. Lunghi G, et al. Among authors: liessi n. Cells. 2022 Jul 29;11(15):2343. doi: 10.3390/cells11152343. Cells. 2022. PMID: 35954187 Free PMC article.

8

Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.

Liessi N, Cichero E, Pesce E, Arkel M, Salis A, Tomati V, Paccagnella M, Damonte G, Tasso B, Galietta LJV, Pedemonte N, Fossa P, Millo E. Liessi N, et al. Eur J Med Chem. 2018 Jan 20;144:179-200. doi: 10.1016/j.ejmech.2017.12.030. Epub 2017 Dec 8. Eur J Med Chem. 2018. PMID: 29272749

9

Synthesis and Structure-activity Relationship of Aminoarylthiazole Derivatives as Potential Potentiators of the Chloride Transport Defect in Cystic Fibrosis.

Liessi N, Pesce E, Salis A, Damonte G, Tasso B, Cichero E, Pedemonte N, Millo E. Liessi N, et al. Med Chem. 2021;17(6):646-657. doi: 10.2174/1573406416666200306114300. Med Chem. 2021. PMID: 32141420

10

Molecular Docking and QSAR Studies as Computational Tools Exploring the Rescue Ability of F508del CFTR Correctors.

Righetti G, Casale M, Liessi N, Tasso B, Salis A, Tonelli M, Millo E, Pedemonte N, Fossa P, Cichero E. Righetti G, et al. Among authors: liessi n. Int J Mol Sci. 2020 Oct 29;21(21):8084. doi: 10.3390/ijms21218084. Int J Mol Sci. 2020. PMID: 33138251 Free PMC article.

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