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Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation.
Orth MF, Surdez D, Faehling T, Ehlers AC, Marchetto A, Grossetête S, Volckmann R, Zwijnenburg DA, Gerke JS, Zaidi S, Alonso J, Sastre A, Baulande S, Sill M, Cidre-Aranaz F, Ohmura S, Kirchner T, Hauck SM, Reischl E, Gymrek M, Pfister SM, Strauch K, Koster J, Delattre O, Grünewald TGP. Orth MF, et al. Among authors: koster j. Cell Rep. 2022 Dec 6;41(10):111761. doi: 10.1016/j.celrep.2022.111761. Cell Rep. 2022. PMID: 36476851 Free PMC article.
Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations.
Okonechnikov K, Schrimpf D, Koster J, Sievers P, Milde T, Sahm F, Jones DTW, von Deimling A, Pfister SM, Kool M, Korshunov A. Okonechnikov K, et al. Among authors: koster j. Acta Neuropathol. 2024 Jun 7;147(1):95. doi: 10.1007/s00401-024-02746-6. Acta Neuropathol. 2024. PMID: 38847845
A consensus molecular subtypes classification strategy for clinical colorectal cancer tissues.
de Back TR, Wu T, Schafrat PJ, Ten Hoorn S, Tan M, He L, van Hooff SR, Koster J, Nijman LE, Vink GR, Beumer IJ, Elbers CC, Lenos KJ, Sommeijer DW, Wang X, Vermeulen L. de Back TR, et al. Among authors: koster j. Life Sci Alliance. 2024 May 23;7(8):e202402730. doi: 10.26508/lsa.202402730. Print 2024 Aug. Life Sci Alliance. 2024. PMID: 38782602 Free PMC article.
Identifying colorectal cancer-specific vulnerabilities in the Wnt-driven long non-coding transcriptome.
Schwarzmueller LJ, Adam RS, Moreno LF, Nijman LE, Logiantara A, Eleonora S, Bril O, Vromans S, de Groot NE, Giugliano FP, Stepanova E, Muncan V, Elbers CC, Lenos KJ, Zwijnenburg DA, van Eijndhoven MAJ, Pegtel DM, van Neerven SM, Loayza-Puch F, Dadali T, Broom WJ, Maier MA, Koster J, Vermeulen L, Léveillé N. Schwarzmueller LJ, et al. Among authors: koster j. Gut. 2024 Nov 19:gutjnl-2024-332752. doi: 10.1136/gutjnl-2024-332752. Online ahead of print. Gut. 2024. PMID: 39562049 Free article.
Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors.
Metselaar DS, Meel MH, Goulding JR, du Chatinier A, Rigamonti L, Waranecki P, Geisemeyer N, de Gooijer MC, Breur M, Koster J, Veldhuijzen van Zanten SEM, Bugiani M, Franke NE, Reddy A, Wesseling P, Kaspers GJL, Hulleman E. Metselaar DS, et al. Among authors: koster j. Cell Rep Med. 2024 Sep 17;5(9):101700. doi: 10.1016/j.xcrm.2024.101700. Epub 2024 Aug 28. Cell Rep Med. 2024. PMID: 39208799 Free PMC article.
Benefit of adjuvant chemotherapy on recurrence free survival per consensus molecular subtype in stage III colon cancer.
van de Weerd S, Torang A, van den Berg I, Lammers V, van den Bergh S, Brouwer N, Nagtegaal ID, Koopman M, Vink GR, van der Baan FH, van Krieken H, Koster J, Ijzermans JN, Roodhart JML, Medema JP. van de Weerd S, et al. Among authors: koster j. Int J Cancer. 2025 Jan 15;156(2):456-466. doi: 10.1002/ijc.35120. Epub 2024 Aug 8. Int J Cancer. 2025. PMID: 39115332 Free PMC article.
Transcriptome-based classification to predict FOLFIRINOX response in a real-world metastatic pancreatic cancer cohort.
Lansbergen MF, Dings MPG, Manoukian P, Fariña A, Waasdorp C, Hooijer GKJ, Verheij J, Koster J, Zwijnenburg DA, Wilmink JW, Medema JP, Dijk F, van Laarhoven HWM, Bijlsma MF. Lansbergen MF, et al. Among authors: koster j. Transl Res. 2024 Nov;273:137-147. doi: 10.1016/j.trsl.2024.08.002. Epub 2024 Aug 21. Transl Res. 2024. PMID: 39154856 Free article.
869 results