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Ontologizing health systems data at scale: making translational discovery a reality.
Callahan TJ, Stefanski AL, Wyrwa JM, Zeng C, Ostropolets A, Banda JM, Baumgartner WA Jr, Boyce RD, Casiraghi E, Coleman BD, Collins JH, Deakyne Davies SJ, Feinstein JA, Lin AY, Martin B, Matentzoglu NA, Meeker D, Reese J, Sinclair J, Taneja SB, Trinkley KE, Vasilevsky NA, Williams AE, Zhang XA, Denny JC, Ryan PB, Hripcsak G, Bennett TD, Haendel MA, Robinson PN, Hunter LE, Kahn MG. Callahan TJ, et al. Among authors: denny jc. NPJ Digit Med. 2023 May 19;6(1):89. doi: 10.1038/s41746-023-00830-x. NPJ Digit Med. 2023. PMID: 37208468 Free PMC article.
PheWAS analysis on large-scale biobank data with PheTK.
Tran TC, Schlueter DJ, Zeng C, Mo H, Carroll RJ, Denny JC. Tran TC, et al. Among authors: denny jc. Bioinformatics. 2024 Dec 9:btae719. doi: 10.1093/bioinformatics/btae719. Online ahead of print. Bioinformatics. 2024. PMID: 39657951
The "All of Us" Research Program.
All of Us Research Program Investigators; Denny JC, Rutter JL, Goldstein DB, Philippakis A, Smoller JW, Jenkins G, Dishman E. All of Us Research Program Investigators, et al. Among authors: denny jc. N Engl J Med. 2019 Aug 15;381(7):668-676. doi: 10.1056/NEJMsr1809937. N Engl J Med. 2019. PMID: 31412182 Free PMC article.
Author Correction: Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.
Liu L, Khan A, Sanchez-Rodriguez E, Zanoni F, Li Y, Steers N, Balderes O, Zhang J, Krithivasan P, LeDesma RA, Fischman C, Hebbring SJ, Harley JB, Moncrieffe H, Kottyan LC, Namjou-Khales B, Walunas TL, Knevel R, Raychaudhuri S, Karlson EW, Denny JC, Stanaway IB, Crosslin D, Rauen T, Floege J, Eitner F, Moldoveanu Z, Reily C, Knoppova B, Hall S, Sheff JT, Julian BA, Wyatt RJ, Suzuki H, Xie J, Chen N, Zhou X, Zhang H, Hammarström L, Viktorin A, Magnusson PKE, Shang N, Hripcsak G, Weng C, Rundek T, Elkind MSV, Oelsner EC, Barr RG, Ionita-Laza I, Novak J, Gharavi AG, Kiryluk K. Liu L, et al. Among authors: denny jc. Nat Commun. 2023 Feb 6;14(1):655. doi: 10.1038/s41467-023-36340-3. Nat Commun. 2023. PMID: 36746961 Free PMC article. No abstract available.
Design and Implementation of the All of Us Research Program COVID-19 Participant Experience (COPE) Survey.
Schulkey CE, Litwin TR, Ellsworth G, Sansbury H, Ahmedani BK, Choi KW, Cronin RM, Kloth Y, Ashbeck AW, Sutherland S, Mapes BM, Begale M, Bhat G, King P, Marginean K, Wolfe KA, Kouame A, Raquel C, Ratsimbazafy F, Bornemeier Z, Neumeier K, Baskir R, Gebo KA, Denny J, Smoller JW, Garriock HA. Schulkey CE, et al. Am J Epidemiol. 2023 Jun 2;192(6):972-986. doi: 10.1093/aje/kwad035. Am J Epidemiol. 2023. PMID: 36799620 Free PMC article.
Phenome-Wide Association of APOE Alleles in the All of Us Research Program.
Khajouei E, Ghisays V, Piras IS, Martinez KL, Naymik M, Ngo P, Tran TC, Denny JC, Wheeler TJ, Huentelman MJ, Reiman EM, Karnes JH. Khajouei E, et al. Among authors: denny jc. medRxiv [Preprint]. 2024 Sep 4:2024.09.04.24313010. doi: 10.1101/2024.09.04.24313010. medRxiv. 2024. PMID: 39281754 Free PMC article. Preprint.
Integrated clinical risk prediction of type 2 diabetes with a multifactorial polygenic risk score.
Ritchie SC, Taylor HJ, Liang Y, Manikpurage HD, Pennells L, Foguet C, Abraham G, Gibson JT, Jiang X, Liu Y, Xu Y, Kim LG, Mahajan A, McCarthy MI, Kaptoge S, Lambert SA, Wood A, Sim X, Collins FS, Denny JC, Danesh J, Butterworth AS, Di Angelantonio E, Inouye M. Ritchie SC, et al. Among authors: denny jc. medRxiv [Preprint]. 2024 Sep 23:2024.08.22.24312440. doi: 10.1101/2024.08.22.24312440. medRxiv. 2024. PMID: 39228710 Free PMC article. Preprint.
435 results