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Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with MLL rearrangement or NPM1 mutation to venetoclax.
Rausch J, Dzama MM, Dolgikh N, Stiller HL, Bohl SR, Lahrmann C, Kunz K, Kessler L, Echchannaoui H, Chen CW, Kindler T, Döhner K, Burrows F, Theobald M, Sasca D, Kühn MWM. Rausch J, et al. Among authors: kunz k. Haematologica. 2023 Oct 1;108(10):2837-2843. doi: 10.3324/haematol.2022.282160. Haematologica. 2023. PMID: 37102614 Free PMC article. No abstract available.
Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition.
Dzama MM, Steiner M, Rausch J, Sasca D, Schönfeld J, Kunz K, Taubert MC, McGeehan GM, Chen CW, Mupo A, Hähnel P, Theobald M, Kindler T, Koche RP, Vassiliou GS, Armstrong SA, Kühn MWM. Dzama MM, et al. Among authors: kunz k. Blood. 2020 Nov 19;136(21):2442-2456. doi: 10.1182/blood.2020005037. Blood. 2020. PMID: 32589720 Free PMC article.
β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance Profiling.
Mathew J, Zhou B, Haney RS, Kunz KA, Do Amaral LS, Roy Chowdhury R, Butler JH, Li H, Chakraborty AJ, Tabassum A, Bremers EK, Merino EF, Coyle R, Lee MCS, Baud D, Brand S, Totrov M, Cassera MB, Carlier PR. Mathew J, et al. Among authors: kunz ka. ACS Infect Dis. 2024 Nov 8;10(11):3951-3962. doi: 10.1021/acsinfecdis.4c00653. Epub 2024 Oct 28. ACS Infect Dis. 2024. PMID: 39466084
Synthesis of N2-Substituted 1,2,3-Triazoles.
Kunz KA, Springer BL, Klahn P, Aldemir H, Mohr F, Kirsch SF. Kunz KA, et al. Org Lett. 2024 Oct 18;26(41):8816-8820. doi: 10.1021/acs.orglett.4c03204. Epub 2024 Oct 8. Org Lett. 2024. PMID: 39378272
The mediating role of self-efficacy in the relationship between past professional training and burnout resilience in medical education: a multicentre cross-sectional study.
Erschens R, Schröpel C, Herrmann-Werner A, Junne F, Listunova L, Heinzmann A, Keis O, Schüttpelz-Brauns K, Herpertz SC, Kunz K, Zipfel S, Festl-Wietek T. Erschens R, et al. Among authors: kunz k. BMC Med Educ. 2024 Aug 14;24(1):875. doi: 10.1186/s12909-024-05854-9. BMC Med Educ. 2024. PMID: 39143612 Free PMC article.
How professional and academic pre-qualifications relate to success in medical education: Results of a multicentre study in Germany.
Schröpel C, Festl-Wietek T, Herrmann-Werner A, Wittenberg T, Schüttpelz-Brauns K, Heinzmann A, Keis O, Listunova L, Kunz K, Böckers T, Herpertz SC, Zipfel S, Erschens R. Schröpel C, et al. Among authors: kunz k. PLoS One. 2024 Mar 8;19(3):e0296982. doi: 10.1371/journal.pone.0296982. eCollection 2024. PLoS One. 2024. PMID: 38457481 Free PMC article.
Simvastatin in Critically Ill Patients with Covid-19.
REMAP-CAP Investigators; Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Horvat C, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF. REMAP-CAP Investigators, et al. N Engl J Med. 2023 Dec 21;389(25):2341-2354. doi: 10.1056/NEJMoa2309995. Epub 2023 Oct 25. N Engl J Med. 2023. PMID: 37888913 Free PMC article. Clinical Trial.
128 results