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An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia.
Cornelius DC, Amaral LM, Harmon A, Wallace K, Thomas AJ, Campbell N, Scott J, Herse F, Haase N, Moseley J, Wallukat G, Dechend R, LaMarca B. Cornelius DC, et al. Among authors: campbell n. Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15;309(8):R884-91. doi: 10.1152/ajpregu.00154.2015. Epub 2015 Aug 19. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 26290102 Free PMC article.
Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT1-AA in response to adoptive transfer of CD4+ T lymphocytes from RUPP rats.
Cornelius DC, Castillo J, Porter J, Amaral LM, Campbell N, Paige A, Thomas AJ, Harmon A, Cunningham MW Jr, Wallace K, Herse F, Wallukat G, Dechend R, LaMarca B. Cornelius DC, et al. Among authors: campbell n. Am J Physiol Regul Integr Comp Physiol. 2015 Nov 15;309(10):R1243-50. doi: 10.1152/ajpregu.00273.2015. Epub 2015 Aug 26. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 26310940 Free PMC article.
Reduced uterine perfusion pressure T-helper 17 cells cause pathophysiology associated with preeclampsia during pregnancy.
Cornelius DC, Amaral LM, Wallace K, Campbell N, Thomas AJ, Scott J, Herse F, Wallukat G, Dechend R, LaMarca B. Cornelius DC, et al. Among authors: campbell n. Am J Physiol Regul Integr Comp Physiol. 2016 Dec 1;311(6):R1192-R1199. doi: 10.1152/ajpregu.00117.2016. Epub 2016 Oct 26. Am J Physiol Regul Integr Comp Physiol. 2016. PMID: 27784685 Free PMC article.
Vitamin D supplementation reduces some AT1-AA-induced downstream targets implicated in preeclampsia including hypertension.
Faulkner JL, Amaral LM, Cornelius DC, Cunningham MW, Ibrahim T, Heep A, Campbell N, Usry N, Wallace K, Herse F, Dechend R, LaMarca B. Faulkner JL, et al. Among authors: campbell n. Am J Physiol Regul Integr Comp Physiol. 2017 Jan 1;312(1):R125-R131. doi: 10.1152/ajpregu.00218.2016. Epub 2016 Nov 30. Am J Physiol Regul Integr Comp Physiol. 2017. PMID: 27903510 Free PMC article.
Renal natural killer cell activation and mitochondrial oxidative stress; new mechanisms in AT1-AA mediated hypertensive pregnancy.
Cunningham MW Jr, Vaka VR, McMaster K, Ibrahim T, Cornelius DC, Amaral L, Campbell N, Wallukat G, McDuffy S, Usry N, Dechend R, LaMarca B. Cunningham MW Jr, et al. Among authors: campbell n. Pregnancy Hypertens. 2019 Jan;15:72-77. doi: 10.1016/j.preghy.2018.11.004. Epub 2018 Nov 30. Pregnancy Hypertens. 2019. PMID: 30825931 Free PMC article.
CD4+ T cells cause renal and placental mitochondrial oxidative stress as mechanisms of hypertension in response to placental ischemia.
Deer E, Reeve KE, Amaral L, Vaka VR, Franks M, Campbell N, Fitzgerald S, Herrock O, Ibrahim T, Cornelius D, LaMarca B. Deer E, et al. Among authors: campbell n. Am J Physiol Renal Physiol. 2021 Jan 1;320(1):F47-F54. doi: 10.1152/ajprenal.00398.2020. Epub 2020 Nov 16. Am J Physiol Renal Physiol. 2021. PMID: 33196321 Free PMC article.
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