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Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.
Bharadwaj R, Lusi CF, Mashayekh S, Nagar A, Subbarao M, Kane GI, Wodzanowski KA, Brown AR, Okuda K, Monahan A, Paik D, Nandy A, Anonick MV, Goldman WE, Kanneganti TD, Orzalli MH, Grimes CL, Atukorale PU, Silverman N. Bharadwaj R, et al. Among authors: orzalli mh. Immunity. 2023 May 9;56(5):998-1012.e8. doi: 10.1016/j.immuni.2023.04.001. Epub 2023 Apr 27. Immunity. 2023. PMID: 37116499 Free PMC article.
Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces.
Maeda K, Zachos NC, Orzalli MH, Schmieder SS, Chang D, Bugda Gwilt K, Doucet M, Baetz NW, Lee S, Crawford SE, Estes MK, Kagan JC, Turner JR, Lencer WI. Maeda K, et al. Among authors: orzalli mh. Cell Host Microbe. 2022 Feb 9;30(2):216-231.e5. doi: 10.1016/j.chom.2021.12.011. Cell Host Microbe. 2022. PMID: 35143768 Free PMC article.
21 results