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Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: weissman kj. Nat Rev Chem. 2021 Oct;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 37118182 Review.
Autonomous folding of interdomain regions of a modular polyketide synthase.
Richter CD, Stanmore DA, Miguel RN, Moncrieffe MC, Tran L, Brewerton S, Meersman F, Broadhurst RW, Weissman KJ. Richter CD, et al. Among authors: weissman kj. FEBS J. 2007 May;274(9):2196-209. doi: 10.1111/j.1742-4658.2007.05757.x. Epub 2007 Apr 5. FEBS J. 2007. PMID: 17419733 Free article.
The Thioesterase of the Erythromycin-Producing Polyketide Synthase: Influence of Acyl Chain Structure on the Mode of Release of Substrate Analogues from the Acyl Enzyme Intermediates.
Weissman KJ, Smith CJ, Hanefeld U, Aggarwal R, Bycroft M, Staunton J, Leadlay PF. Weissman KJ, et al. Angew Chem Int Ed Engl. 1998 Jun 5;37(10):1437-1440. doi: 10.1002/(SICI)1521-3773(19980605)37:10<1437::AID-ANIE1437>3.0.CO;2-7. Angew Chem Int Ed Engl. 1998. PMID: 29710889
Polyketide biosynthesis: a millennium review.
Staunton J, Weissman KJ. Staunton J, et al. Among authors: weissman kj. Nat Prod Rep. 2001 Aug;18(4):380-416. doi: 10.1039/a909079g. Nat Prod Rep. 2001. PMID: 11548049 Review. No abstract available.
79 results