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Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1+ monocytes-derived macrophages.
Yuan X, Qin X, Takemoto K, Zhao J, Sanderson M, Xu X, Zhang Y, Helke KL, Jacobs Wolf B, Guthridge JM, James JA, Zhou X, Assassi S, Feghali-Bostwick C, Wang D, Sun L, Tsao BP. Yuan X, et al. Among authors: jacobs wolf b. Ann Rheum Dis. 2024 Sep 24:ard-2024-226034. doi: 10.1136/ard-2024-226034. Online ahead of print. Ann Rheum Dis. 2024. PMID: 39299725
Big tau aggregation disrupts microtubule tyrosination and causes myocardial diastolic dysfunction: from discovery to therapy.
Luciani M, Montalbano M, Troncone L, Bacchin C, Uchida K, Daniele G, Jacobs Wolf B, Butler HM, Kiel J, Berto S, Gensemer C, Moore K, Morningstar J, Diteepeng T, Albayram O, Abisambra JF, Norris RA, Di Salvo TG, Prosser B, Kayed R, Del Monte F. Luciani M, et al. Among authors: jacobs wolf b. Eur Heart J. 2023 May 1;44(17):1560-1570. doi: 10.1093/eurheartj/ehad205. Eur Heart J. 2023. PMID: 37122097 Free PMC article.