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Page 1
Neuronal human BACE1 knockin induces systemic diabetes in mice.
Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield PD, Doherty MK, Mingarelli M, Welch A, Riedel G, Delibegovic M, Platt B. Plucińska K, et al. Among authors: platt b. Diabetologia. 2016 Jul;59(7):1513-1523. doi: 10.1007/s00125-016-3960-1. Epub 2016 May 2. Diabetologia. 2016. PMID: 27138913 Free PMC article.
The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice.
Dekeryte R, Franklin Z, Hull C, Croce L, Kamli-Salino S, Helk O, Hoffmann PA, Yang Z, Riedel G, Delibegovic M, Platt B. Dekeryte R, et al. Among authors: platt b. Biochim Biophys Acta Mol Basis Dis. 2021 Jul 1;1867(7):166149. doi: 10.1016/j.bbadis.2021.166149. Epub 2021 Apr 20. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33892080 Free article.
Susceptibility to diet-induced obesity and glucose intolerance in the APP (SWE)/PSEN1 (A246E) mouse model of Alzheimer's disease is associated with increased brain levels of protein tyrosine phosphatase 1B (PTP1B) and retinol-binding protein 4 (RBP4), and basal phosphorylation of S6 ribosomal protein.
Mody N, Agouni A, McIlroy GD, Platt B, Delibegovic M. Mody N, et al. Among authors: platt b. Diabetologia. 2011 Aug;54(8):2143-51. doi: 10.1007/s00125-011-2160-2. Epub 2011 May 3. Diabetologia. 2011. PMID: 21538175
292 results