Lohmueller J - Search Results

1

Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting.

Ruffo E, Butchy AA, Tivon Y, So V, Kvorjak M, Parikh A, Adams EL, Miskov-Zivanov N, Finn OJ, Deiters A, Lohmueller J. Ruffo E, et al. Among authors: lohmueller j. Nat Commun. 2023 May 9;14(1):2463. doi: 10.1038/s41467-023-37863-5. Nat Commun. 2023. PMID: 37160880 Free PMC article.

2

Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential.

Lohmueller JJ, Sato S, Popova L, Chu IM, Tucker MA, Barberena R, Innocenti GM, Cudic M, Ham JD, Cheung WC, Polakiewicz RD, Finn OJ. Lohmueller JJ, et al. Sci Rep. 2016 Aug 22;6:31740. doi: 10.1038/srep31740. Sci Rep. 2016. PMID: 27545199 Free PMC article.

3

Current modalities in cancer immunotherapy: Immunomodulatory antibodies, CARs and vaccines.

Lohmueller J, Finn OJ. Lohmueller J, et al. Pharmacol Ther. 2017 Oct;178:31-47. doi: 10.1016/j.pharmthera.2017.03.008. Epub 2017 Mar 16. Pharmacol Ther. 2017. PMID: 28322974 Free PMC article. Review.

4

Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer.

Cascio S, Faylo JL, Sciurba JC, Xue J, Ranganathan S, Lohmueller JJ, Beatty PL, Finn OJ. Cascio S, et al. Among authors: lohmueller jj. Oncotarget. 2017 Oct 27;8(62):105284-105298. doi: 10.18632/oncotarget.22168. eCollection 2017 Dec 1. Oncotarget. 2017. PMID: 29285251 Free PMC article.

5

mSA2 affinity-enhanced biotin-binding CAR T cells for universal tumor targeting.

Lohmueller JJ, Ham JD, Kvorjak M, Finn OJ. Lohmueller JJ, et al. Oncoimmunology. 2017 Oct 26;7(1):e1368604. doi: 10.1080/2162402X.2017.1368604. eCollection 2017. Oncoimmunology. 2017. PMID: 29296519 Free PMC article.

6

The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse.

Kataoka S, Manandhar P, Lee J, Workman CJ, Banerjee H, Szymczak-Workman AL, Kvorjak M, Lohmueller J, Kane LP. Kataoka S, et al. Among authors: lohmueller j. Sci Signal. 2021 Jun 15;14(687):eaba0717. doi: 10.1126/scisignal.aba0717. Sci Signal. 2021. PMID: 34131021 Free PMC article.

7

Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors.

Lontos K, Wang Y, Joshi SK, Frisch AT, Watson MJ, Kumar A, Menk AV, Wang Y, Cumberland R, Lohmueller J, Carrizosa E, Boyerinas B, Delgoffe GM. Lontos K, et al. Among authors: lohmueller j. J Immunother Cancer. 2023 Mar;11(3):e006522. doi: 10.1136/jitc-2022-006522. J Immunother Cancer. 2023. PMID: 36914208 Free PMC article.

8

Conditional Control of Universal CAR T Cells by Cleavable OFF-Switch Adaptors.

Kvorjak M, Ruffo E, Tivon Y, So V, Parikh A, Deiters A, Lohmueller J. Kvorjak M, et al. Among authors: lohmueller j. ACS Synth Biol. 2023 Oct 20;12(10):2996-3007. doi: 10.1021/acssynbio.3c00320. Epub 2023 Oct 4. ACS Synth Biol. 2023. PMID: 37791909 Free PMC article.

9

CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays.

Cho Y, Laird MS, Bishop T, Li R, Jazwinska DE, Ruffo E, Lohmueller J, Zervantonakis IK. Cho Y, et al. Among authors: lohmueller j. APL Bioeng. 2024 Jul 23;8(3):036105. doi: 10.1063/5.0207941. eCollection 2024 Sep. APL Bioeng. 2024. PMID: 39049849 Free PMC article.

10

Synthetic biology in mammalian cells: next generation research tools and therapeutics.

Lienert F, Lohmueller JJ, Garg A, Silver PA. Lienert F, et al. Among authors: lohmueller jj. Nat Rev Mol Cell Biol. 2014 Feb;15(2):95-107. doi: 10.1038/nrm3738. Epub 2014 Jan 17. Nat Rev Mol Cell Biol. 2014. PMID: 24434884 Free PMC article. Review.

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