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Fortuitous somatic mutations during antibody evolution endow broad neutralization against SARS-CoV-2 Omicron variants.
Wu J, Chen Z, Gao Y, Wang Z, Wang J, Chiang BY, Zhou Y, Han Y, Zhan W, Xie M, Jiang W, Zhang X, Hao A, Xia A, He J, Xue S, Mayer CT, Wu F, Wang B, Zhang L, Sun L, Wang Q. Wu J, et al. Among authors: zhang l, zhang x. Cell Rep. 2023 May 30;42(5):112503. doi: 10.1016/j.celrep.2023.112503. Epub 2023 May 3. Cell Rep. 2023. PMID: 37178120 Free PMC article.
An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Liu Z, Xu W, Chen Z, Fu W, Zhan W, Gao Y, Zhou J, Zhou Y, Wu J, Wang Q, Zhang X, Hao A, Wu W, Zhang Q, Li Y, Fan K, Chen R, Jiang Q, Mayer CT, Schoofs T, Xie Y, Jiang S, Wen Y, Yuan Z, Wang K, Lu L, Sun L, Wang Q. Liu Z, et al. Among authors: zhang q, zhang x. Protein Cell. 2022 Sep;13(9):655-675. doi: 10.1007/s13238-021-00871-6. Epub 2021 Sep 23. Protein Cell. 2022. PMID: 34554412 Free PMC article.
Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Li C, Zhan W, Yang Z, Tu C, Hu G, Zhang X, Song W, Du S, Zhu Y, Huang K, Kong Y, Zhang M, Mao Q, Gu X, Zhang Y, Xie Y, Deng Q, Song Y, Chen Z, Lu L, Jiang S, Wu Y, Sun L, Ying T. Li C, et al. Among authors: zhang m, zhang x, zhang y. Cell. 2022 Apr 14;185(8):1389-1401.e18. doi: 10.1016/j.cell.2022.03.009. Epub 2022 Mar 10. Cell. 2022. PMID: 35344711 Free PMC article.
A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Wang Y, Zhan W, Liu J, Wang Y, Zhang X, Zhang M, Han L, Ma Y, Lu L, Wen Y, Chen Z, Zhao J, Wu F, Sun L, Huang J. Wang Y, et al. Among authors: zhang m, zhang x. Cell Res. 2022 Sep;32(9):862-865. doi: 10.1038/s41422-022-00684-0. Epub 2022 Jun 29. Cell Res. 2022. PMID: 35768499 Free PMC article. No abstract available.
Fortuitous Somatic Mutations during Antibody Evolution Endow Broad Neutralization against SARS-CoV-2 Omicron Variants.
Wu J, Chen Z, Gao Y, Wang Z, Wang J, Chiang BY, Zhou Y, Han Y, Zhan W, Xie M, Jiang W, Zhang X, Hao A, Xia A, He J, Xue S, Mayer CT, Wu F, Wang B, Zhang L, Sun L, Wang Q. Wu J, et al. Among authors: zhang l, zhang x. bioRxiv [Preprint]. 2022 Dec 13:2022.12.12.520172. doi: 10.1101/2022.12.12.520172. bioRxiv. 2022. Update in: Cell Rep. 2023 May 30;42(5):112503. doi: 10.1016/j.celrep.2023.112503 PMID: 36561175 Free PMC article. Updated. Preprint.
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