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Page 1
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Kan WL, Dhagat U, Kaufmann KB, Hercus TR, Nero TL, Zeng AGX, Toubia J, Barry EF, Broughton SE, Gomez GA, Benard BA, Dottore M, Cheung Tung Shing KS, Boutzen H, Samaraweera SE, Simpson KJ, Jin L, Goodall GJ, Begley CG, Thomas D, Ekert PG, Tvorogov D, D'Andrea RJ, Dick JE, Parker MW, Lopez AF. Kan WL, et al. Among authors: samaraweera se. Cancer Discov. 2023 Aug 4;13(8):1922-1947. doi: 10.1158/2159-8290.CD-22-1396. Cancer Discov. 2023. PMID: 37191437 Free PMC article.
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
Powell JA, Lewis AC, Zhu W, Toubia J, Pitman MR, Wallington-Beddoe CT, Moretti PA, Iarossi D, Samaraweera SE, Cummings N, Ramshaw HS, Thomas D, Wei AH, Lopez AF, D'Andrea RJ, Lewis ID, Pitson SM. Powell JA, et al. Among authors: samaraweera se. Blood. 2017 Feb 9;129(6):771-782. doi: 10.1182/blood-2016-06-720433. Epub 2016 Dec 12. Blood. 2017. PMID: 27956387 Free PMC article.
Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia.
Maung KZY, Leo PJ, Bassal M, Casolari DA, Gray JX, Bray SC, Pederson S, Singhal D, Samaraweera SE, Nguyen T, Cildir G, Marshall M, Ewing A, Duncan EL, Brown MA, Saal R, Tergaonkar V, To LB, Marlton P, Gill D, Lewis I, Deans AJ, Brown AL, D'Andrea RJ, Gonda TJ. Maung KZY, et al. Among authors: samaraweera se. Blood Cancer J. 2018 Jun 1;8(6):50. doi: 10.1038/s41408-018-0090-7. Blood Cancer J. 2018. PMID: 29891941 Free PMC article. No abstract available.
Childhood acute myeloid leukemia shows a high level of germline predisposition.
Samaraweera SE, Wang PPS, Li KL, Casolari DA, Feng J, Pinese M, Maung KZY, Leo P, Cowley M, Perkins K, Smith AM, Ellis J, Wee A, Hiwase DK, Scott HS, Schreiber AW, Brown AL, Deans AJ, Ross DM, Moore AS, Gonda TJ, Hahn CN, D'Andrea RJ. Samaraweera SE, et al. Blood. 2021 Dec 2;138(22):2293-2298. doi: 10.1182/blood.2021012666. Blood. 2021. PMID: 34521114 Free article. No abstract available.
Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.
Bassal MA, Samaraweera SE, Lim K, Benard BA, Bailey S, Kaur S, Leo P, Toubia J, Thompson-Peach C, Nguyen T, Maung KZY, Casolari DA, Iarossi DG, Pagani IS, Powell J, Pitson S, Natera S, Roessner U, Lewis ID, Brown AL, Tenen DG, Robinson N, Ross DM, Majeti R, Gonda TJ, Thomas D, D'Andrea RJ. Bassal MA, et al. Among authors: samaraweera se. Nat Commun. 2022 May 12;13(1):2614. doi: 10.1038/s41467-022-30223-9. Nat Commun. 2022. PMID: 35551192 Free PMC article.
Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.
Bassal MA, Samaraweera SE, Lim K, Benard BA, Bailey S, Kaur S, Leo P, Toubia J, Thompson-Peach C, Nguyen T, Maung KZY, Casolari DA, Iarossi DG, Pagani IS, Powell J, Pitson S, Natera S, Roessner U, Lewis ID, Brown AL, Tenen DG, Robinson N, Ross DM, Majeti R, Gonda TJ, Thomas D, D'Andrea RJ. Bassal MA, et al. Among authors: samaraweera se. Nat Commun. 2022 Jul 15;13(1):4131. doi: 10.1038/s41467-022-31952-7. Nat Commun. 2022. PMID: 35840577 Free PMC article. No abstract available.
Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia.
Conn VM, Gabryelska M, Toubia J, Kirk K, Gantley L, Powell JA, Cildir G, Marri S, Liu R, Stringer BW, Townley S, Webb ST, Lin H, Samaraweera SE, Bailey S, Moore AS, Maybury M, Liu D, Colella AD, Chataway T, Wallington-Gates CT, Walters L, Sibbons J, Selth LA, Tergaonkar V, D'Andrea RJ, Pitson SM, Goodall GJ, Conn SJ. Conn VM, et al. Among authors: samaraweera se. Cancer Cell. 2023 Jul 10;41(7):1309-1326.e10. doi: 10.1016/j.ccell.2023.05.002. Epub 2023 Jun 8. Cancer Cell. 2023. PMID: 37295428 Free article.
Novel modes of MPL activation in triple-negative myeloproliferative neoplasms.
Samaraweera SE, Geukens T, Casolari DA, Nguyen T, Sun C, Bailey S, Moore S, Feng J, Schreiber AW, Parker WT, Brown AL, Butcher C, Bardy PG, Osborn M, Scott HS, Talaulikar D, Grove CS, Hahn CN, D'Andrea RJ, Ross DM. Samaraweera SE, et al. Pathology. 2023 Feb;55(1):77-85. doi: 10.1016/j.pathol.2022.05.015. Epub 2022 Aug 5. Pathology. 2023. PMID: 36031433
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