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The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression.
Mas G, Man N, Nakata Y, Martinez-Caja C, Karl D, Beckedorff F, Tamiro F, Chen C, Duffort S, Itonaga H, Mookhtiar AK, Kunkalla K, Valencia AM, Collings CK, Kadoch C, Vega F, Kogan SC, Shiekhattar R, Morey L, Bilbao D, Nimer SD. Mas G, et al. Among authors: shiekhattar r. J Clin Invest. 2023 Jul 3;133(13):e158419. doi: 10.1172/JCI158419. J Clin Invest. 2023. PMID: 37200093 Free PMC article.
Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia.
Brabson JP, Leesang T, Yap YS, Wang J, Lam MQ, Fang B, Dolgalev I, Barbieri DA, Strippoli V, Bañuelos CP, Mohammad S, Lyon P, Chaudhry S, Donich D, Swirski A, Roberts E, Diaz I, Karl D, Dos Santos HG, Shiekhattar R, Neel BG, Nimer SD, Verdun RE, Bilbao D, Figueroa ME, Cimmino L. Brabson JP, et al. Among authors: shiekhattar r. Cell Rep. 2023 Jan 31;42(1):112027. doi: 10.1016/j.celrep.2023.112027. Epub 2023 Jan 23. Cell Rep. 2023. PMID: 36848231 Free PMC article.
Neuronal differentiation requires BRAT1 complex to remove REST from chromatin.
Dokaneheifard S, Gomes Dos Santos H, Guiselle Valencia M, Arigela H, Edupuganti RR, Shiekhattar R. Dokaneheifard S, et al. Among authors: shiekhattar r. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2318740121. doi: 10.1073/pnas.2318740121. Epub 2024 May 28. Proc Natl Acad Sci U S A. 2024. PMID: 38805275 Free PMC article.
PRAME induces genomic instability in uveal melanoma.
Kurtenbach S, Sanchez MI, Kuznetsoff J, Rodriguez DA, Weich N, Dollar J, Cruz A, Kurtenbach S, Field MG, Durante MA, Decatur C, Sorouri M, Lai F, Shiekhattar R, Pelaez D, Correa ZM, Verdun RE, Harbour JW. Kurtenbach S, et al. Among authors: shiekhattar r. Res Sq [Preprint]. 2023 Apr 26:rs.3.rs-2861359. doi: 10.21203/rs.3.rs-2861359/v1. Res Sq. 2023. Update in: Oncogene. 2024 Feb;43(8):555-565. doi: 10.1038/s41388-023-02887-0 PMID: 37162820 Free PMC article. Updated. Preprint.
PRAME induces genomic instability in uveal melanoma.
Kurtenbach S, Sanchez MI, Kuznetsoff J, Rodriguez DA, Weich N, Dollar JJ, Cruz A, Kurtenbach S, Field MG, Durante MA, Decatur C, Sorouri M, Lai F, Yenisehirli G, Fang B, Shiekhattar R, Pelaez D, Correa ZM, Verdun RE, Harbour JW. Kurtenbach S, et al. Among authors: shiekhattar r. Oncogene. 2024 Feb;43(8):555-565. doi: 10.1038/s41388-023-02887-0. Epub 2023 Nov 29. Oncogene. 2024. PMID: 38030788 Free PMC article.
The Integrator complex regulates microRNA abundance through RISC loading.
Kirstein N, Dokaneheifard S, Cingaram PR, Valencia MG, Beckedorff F, Gomes Dos Santos H, Blumenthal E, Tayari MM, Gaidosh GS, Shiekhattar R. Kirstein N, et al. Among authors: shiekhattar r. Sci Adv. 2023 Feb 10;9(6):eadf0597. doi: 10.1126/sciadv.adf0597. Epub 2023 Feb 10. Sci Adv. 2023. PMID: 36763664 Free PMC article.
136 results