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Tissue-resident, extravascular Ly6c- monocytes are critical for inflammation in the synovium.
Montgomery AB, Chen SY, Wang Y, Gadhvi G, Mayr MG, Cuda CM, Dominguez S, Moradeke Makinde HK, Gurra MG, Misharin AV, Mandelin AM, Ruderman EM, Thakrar A, Brar S, Carns M, Aren K, Akbarpour M, Filer A, Nayar S, Teososio A, Major T, Bharat A, Budinger GRS, Winter DR, Perlman H. Montgomery AB, et al. Among authors: carns m. Cell Rep. 2023 May 30;42(5):112513. doi: 10.1016/j.celrep.2023.112513. Epub 2023 May 18. Cell Rep. 2023. PMID: 37204925 Free PMC article.
A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) gene and systemic sclerosis.
Marangoni RG, Korman BD, Allanore Y, Dieude P, Armstrong LL, Rzhetskaya M, Hinchcliff M, Carns M, Podlusky S, Shah SJ, Ruiz B, Hachulla E, Tiev K, Cracowski JL, Varga J, Hayes MG. Marangoni RG, et al. Among authors: carns m. Arthritis Res Ther. 2015 May 19;17(1):128. doi: 10.1186/s13075-015-0641-2. Arthritis Res Ther. 2015. PMID: 25986483 Free PMC article.
Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin.
Hinchcliff M, Toledo DM, Taroni JN, Wood TA, Franks JM, Ball MS, Hoffmann A, Amin SM, Tan AU, Tom K, Nesbeth Y, Lee J, Ma M, Aren K, Carns MA, Pioli PA, Whitfield ML. Hinchcliff M, et al. Among authors: carns ma. J Invest Dermatol. 2018 Jun;138(6):1301-1310. doi: 10.1016/j.jid.2018.01.006. Epub 2018 Jan 31. J Invest Dermatol. 2018. PMID: 29391252 Free PMC article. Clinical Trial.
Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.
Mandelin AM 2nd, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL Jr, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD, Pitzalis C, Parks D, Hughes LB, Geraldino-Pardilla L, Ike R, Phillips K, Wright K, Filer A, Kelly S, Ruderman EM, Morgan V, Abdala-Valencia H, Misharin AV, Budinger GS, Bartom ET, Pope RM, Perlman H, Winter DR. Mandelin AM 2nd, et al. Among authors: carns m. Arthritis Rheumatol. 2018 Jun;70(6):841-854. doi: 10.1002/art.40453. Epub 2018 May 3. Arthritis Rheumatol. 2018. PMID: 29439295 Free PMC article.
Diffuse cardiac fibrosis quantification in early systemic sclerosis by magnetic resonance imaging and correlation with skin fibrosis.
Lee DC, Hinchcliff ME, Sarnari R, Stark MM, Lee J, Koloms K, Hoffmann A, Carns M, Thakrar A, Aren K, Varga J, Aquino A, Carr JC, Benefield BC, Shah SJ. Lee DC, et al. Among authors: carns m. J Scleroderma Relat Disord. 2018 Jun;3(2):159-169. doi: 10.1177/2397198318762888. Epub 2018 Apr 12. J Scleroderma Relat Disord. 2018. PMID: 29808171 Free PMC article.
Increased monocyte count as a cellular biomarker for poor outcomes in fibrotic diseases: a retrospective, multicentre cohort study.
Scott MKD, Quinn K, Li Q, Carroll R, Warsinske H, Vallania F, Chen S, Carns MA, Aren K, Sun J, Koloms K, Lee J, Baral J, Kropski J, Zhao H, Herzog E, Martinez FJ, Moore BB, Hinchcliff M, Denny J, Kaminski N, Herazo-Maya JD, Shah NH, Khatri P. Scott MKD, et al. Among authors: carns ma. Lancet Respir Med. 2019 Jun;7(6):497-508. doi: 10.1016/S2213-2600(18)30508-3. Epub 2019 Mar 29. Lancet Respir Med. 2019. PMID: 30935881 Free PMC article.
Profibrotic Activation of Human Macrophages in Systemic Sclerosis.
Bhandari R, Ball MS, Martyanov V, Popovich D, Schaafsma E, Han S, ElTanbouly M, Orzechowski NM, Carns M, Arroyo E, Aren K, Hinchcliff M, Whitfield ML, Pioli PA. Bhandari R, et al. Among authors: carns m. Arthritis Rheumatol. 2020 Jul;72(7):1160-1169. doi: 10.1002/art.41243. Epub 2020 May 31. Arthritis Rheumatol. 2020. PMID: 32134204 Free PMC article.
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Querrey M, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Lomasney JW, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith SB, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GRS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w. Epub 2021 Jan 11. Nature. 2021. PMID: 33429418 Free PMC article.
Bacterial Superinfection Pneumonia in Patients Mechanically Ventilated for COVID-19 Pneumonia.
Pickens CO, Gao CA, Cuttica MJ, Smith SB, Pesce LL, Grant RA, Kang M, Morales-Nebreda L, Bavishi AA, Arnold JM, Pawlowski A, Qi C, Budinger GRS, Singer BD, Wunderink RG; NU COVID Investigators. Pickens CO, et al. Am J Respir Crit Care Med. 2021 Oct 15;204(8):921-932. doi: 10.1164/rccm.202106-1354OC. Am J Respir Crit Care Med. 2021. PMID: 34409924 Free PMC article.
43 results