Iijima KM - Search Results

1

Alzheimer's Disease-Related Phospho-Tau181 Signals Are Localized to Demyelinated Axons of Parvalbumin-Positive GABAergic Interneurons in an App Knock-In Mouse Model of Amyloid-β Pathology.

Hirota Y, Sakakibara Y, Takei K, Nishijima R, Sekiya M, Iijima KM. Hirota Y, et al. Among authors: iijima km. J Alzheimers Dis. 2023;93(3):1065-1081. doi: 10.3233/JAD-230121. J Alzheimers Dis. 2023. PMID: 37212118 Free PMC article.

2

Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1.

Iijima-Ando K, Sekiya M, Maruko-Otake A, Ohtake Y, Suzuki E, Lu B, Iijima KM. Iijima-Ando K, et al. Among authors: iijima km. PLoS Genet. 2012;8(8):e1002918. doi: 10.1371/journal.pgen.1002918. Epub 2012 Aug 30. PLoS Genet. 2012. PMID: 22952452 Free PMC article.

3

Global analysis of phosphorylation of tau by the checkpoint kinases Chk1 and Chk2 in vitro.

Mendoza J, Sekiya M, Taniguchi T, Iijima KM, Wang R, Ando K. Mendoza J, et al. Among authors: iijima km. J Proteome Res. 2013 Jun 7;12(6):2654-65. doi: 10.1021/pr400008f. Epub 2013 Apr 26. J Proteome Res. 2013. PMID: 23550703 Free PMC article.

4

Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity.

Ando K, Maruko-Otake A, Ohtake Y, Hayashishita M, Sekiya M, Iijima KM. Ando K, et al. Among authors: iijima km. PLoS Genet. 2016 Mar 29;12(3):e1005917. doi: 10.1371/journal.pgen.1005917. eCollection 2016 Mar. PLoS Genet. 2016. PMID: 27023670 Free PMC article.

5

EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila.

Sekiya M, Maruko-Otake A, Hearn S, Sakakibara Y, Fujisaki N, Suzuki E, Ando K, Iijima KM. Sekiya M, et al. Among authors: iijima km. Dev Cell. 2017 Jun 19;41(6):652-664.e5. doi: 10.1016/j.devcel.2017.05.019. Dev Cell. 2017. PMID: 28633019 Free PMC article.

6

Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.

Sakakibara Y, Sekiya M, Fujisaki N, Quan X, Iijima KM. Sakakibara Y, et al. Among authors: iijima km. PLoS Genet. 2018 Jan 22;14(1):e1007196. doi: 10.1371/journal.pgen.1007196. eCollection 2018 Jan. PLoS Genet. 2018. PMID: 29357349 Free PMC article.

7

Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models.

Sekiya M, Wang M, Fujisaki N, Sakakibara Y, Quan X, Ehrlich ME, De Jager PL, Bennett DA, Schadt EE, Gandy S, Ando K, Zhang B, Iijima KM. Sekiya M, et al. Among authors: iijima km. Genome Med. 2018 Mar 29;10(1):26. doi: 10.1186/s13073-018-0530-9. Genome Med. 2018. PMID: 29598827 Free PMC article.

8

Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis.

Sakakibara Y, Sekiya M, Saito T, Saido TC, Iijima KM. Sakakibara Y, et al. Among authors: iijima km. BMC Neurosci. 2018 Jul 28;19(1):46. doi: 10.1186/s12868-018-0446-8. BMC Neurosci. 2018. PMID: 30055565 Free PMC article.

9

Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer's disease.

Sakakibara Y, Sekiya M, Saito T, Saido TC, Iijima KM. Sakakibara Y, et al. Among authors: iijima km. BMC Neurosci. 2019 Mar 20;20(1):13. doi: 10.1186/s12868-019-0496-6. BMC Neurosci. 2019. PMID: 30894120 Free PMC article.

10

Disruption of a RAC1-centred network is associated with Alzheimer's disease pathology and causes age-dependent neurodegeneration.

Kikuchi M, Sekiya M, Hara N, Miyashita A, Kuwano R, Ikeuchi T, Iijima KM, Nakaya A. Kikuchi M, et al. Among authors: iijima km. Hum Mol Genet. 2020 Mar 27;29(5):817-833. doi: 10.1093/hmg/ddz320. Hum Mol Genet. 2020. PMID: 31942999 Free PMC article.

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