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Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and CNS function.
Seeker LA, Bestard-Cuche N, Jäkel S, Kazakou NL, Bøstrand SMK, Wagstaff LJ, Cholewa-Waclaw J, Kilpatrick AM, Van Bruggen D, Kabbe M, Baldivia Pohl F, Moslehi Z, Henderson NC, Vallejos CA, La Manno G, Castelo-Branco G, Williams A. Seeker LA, et al. Among authors: jakel s. Acta Neuropathol Commun. 2023 May 22;11(1):84. doi: 10.1186/s40478-023-01568-z. Acta Neuropathol Commun. 2023. PMID: 37217978 Free PMC article.
Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis.
Falcão AM, van Bruggen D, Marques S, Meijer M, Jäkel S, Agirre E, Samudyata, Floriddia EM, Vanichkina DP, Ffrench-Constant C, Williams A, Guerreiro-Cacais AO, Castelo-Branco G. Falcão AM, et al. Among authors: jakel s. Nat Med. 2018 Dec;24(12):1837-1844. doi: 10.1038/s41591-018-0236-y. Epub 2018 Nov 12. Nat Med. 2018. PMID: 30420755 Free PMC article.
Altered human oligodendrocyte heterogeneity in multiple sclerosis.
Jäkel S, Agirre E, Mendanha Falcão A, van Bruggen D, Lee KW, Knuesel I, Malhotra D, Ffrench-Constant C, Williams A, Castelo-Branco G. Jäkel S, et al. Nature. 2019 Feb;566(7745):543-547. doi: 10.1038/s41586-019-0903-2. Epub 2019 Jan 23. Nature. 2019. PMID: 30747918 Free PMC article.
Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.
Sasmita AO, Depp C, Nazarenko T, Sun T, Siems SB, Ong EC, Nkeh YB, Böhler C, Yu X, Bues B, Evangelista L, Mao S, Morgado B, Wu Z, Ruhwedel T, Subramanian S, Börensen F, Overhoff K, Spieth L, Berghoff SA, Sadleir KR, Vassar R, Eggert S, Goebbels S, Saito T, Saido T, Saher G, Möbius W, Castelo-Branco G, Klafki HW, Wirths O, Wiltfang J, Jäkel S, Yan R, Nave KA. Sasmita AO, et al. Among authors: jakel s. Nat Neurosci. 2024 Sep;27(9):1668-1674. doi: 10.1038/s41593-024-01730-3. Epub 2024 Aug 5. Nat Neurosci. 2024. PMID: 39103558 Free PMC article.
Mapping the glial transcriptome in Huntington's disease using snRNAseq: selective disruption of glial signatures across brain regions.
Bøstrand SMK, Seeker LA, Bestard-Cuche N, Kazakou NL, Jäkel S, Kenkhuis B, Henderson NC, de Bot ST, van Roon-Mom WMC, Priller J, Williams A. Bøstrand SMK, et al. Among authors: jakel s. Acta Neuropathol Commun. 2024 Oct 21;12(1):165. doi: 10.1186/s40478-024-01871-3. Acta Neuropathol Commun. 2024. PMID: 39428482 Free PMC article.
BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions.
Fard MK, van der Meer F, Sánchez P, Cantuti-Castelvetri L, Mandad S, Jäkel S, Fornasiero EF, Schmitt S, Ehrlich M, Starost L, Kuhlmann T, Sergiou C, Schultz V, Wrzos C, Brück W, Urlaub H, Dimou L, Stadelmann C, Simons M. Fard MK, et al. Among authors: jakel s. Sci Transl Med. 2017 Dec 6;9(419):eaam7816. doi: 10.1126/scitranslmed.aam7816. Sci Transl Med. 2017. PMID: 29212715 Free PMC article.
25 results