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Large-scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's disease.
Panyard DJ, McKetney J, Deming YK, Morrow AR, Ennis GE, Jonaitis EM, Van Hulle CA, Yang C, Sung YJ, Ali M, Kollmorgen G, Suridjan I, Bayfield A, Bendlin BB, Zetterberg H, Blennow K, Cruchaga C, Carlsson CM, Johnson SC, Asthana S, Coon JJ, Engelman CD. Panyard DJ, et al. Among authors: sung yj. Alzheimers Dement. 2023 Dec;19(12):5447-5470. doi: 10.1002/alz.13130. Epub 2023 May 22. Alzheimers Dement. 2023. PMID: 37218097 Free PMC article.
Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome.
Gorijala P, Aslam MM, Dang LT, Xicota L, Fernandez MV, Sung YJ, Fan KH, Feingold E, Surace EI, Chhatwal JP, Hom CL; Dominantly Inherited Alzheimer Network (DIAN), the Alzheimer's Disease Neuroimaging Initiative (ADNI); NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigators; Hartley SL, Hassenstab J, Perrin RJ, Mapstone M, Zaman SH, Ances BM, Kamboh MI, Lee JH, Cruchaga C. Gorijala P, et al. Among authors: sung yj. Alzheimers Dement. 2024 Feb;20(2):1038-1049. doi: 10.1002/alz.13506. Epub 2023 Oct 19. Alzheimers Dement. 2024. PMID: 37855447 Free PMC article.
CSF proteomic profiling with amyloid/tau positivity identifies distinctive sex-different alteration of multiple proteins involved in Alzheimer's disease.
Do AN, Ali M, Timsina J, Wang L, Western D, Liu M, Sanford J, Rosende-Roca M, Boada M, Puerta R, Wilson T, Ruiz A, Pastor P; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Wyss-Coray T, Cruchaga C, Sung YJ. Do AN, et al. Among authors: sung yj. medRxiv [Preprint]. 2024 Mar 16:2024.03.15.24304164. doi: 10.1101/2024.03.15.24304164. medRxiv. 2024. PMID: 38559166 Free PMC article. Preprint.
Blood-Based Proteomics for Adult-Onset Focal Dystonias.
Timsina J, Dinasarapu A, Kilic-Berkmen G, Budde J, Sung YJ, Klein AM, Cruchaga C, Jinnah HA. Timsina J, et al. Among authors: sung yj. Ann Neurol. 2024 Jul;96(1):110-120. doi: 10.1002/ana.26929. Epub 2024 Apr 5. Ann Neurol. 2024. PMID: 38578115
Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3.
Panyard DJ, Reus LM, Ali M, Liu J, Deming YK, Lu Q, Kollmorgen G, Carboni M, Wild N, Visser PJ, Bertram L, Zetterberg H, Blennow K, Gobom J, Western D, Sung YJ, Carlsson CM, Johnson SC, Asthana S, Cruchaga C, Tijms BM, Engelman CD, Snyder MP. Panyard DJ, et al. Among authors: sung yj. Alzheimers Dement. 2024 Jul;20(7):5044-5053. doi: 10.1002/alz.13848. Epub 2024 May 29. Alzheimers Dement. 2024. PMID: 38809917 Free PMC article.
Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center.
Fernandez MV, Liu M, Beric A, Johnson M, Cetin A, Patel M, Budde J, Kohlfeld P, Bergmann K, Lowery J, Flynn A, Brock W, Sanchez Montejo B, Gentsch J, Sykora N, Norton J, Gentsch J, Valdez O, Gorijala P, Sanford J, Sun Y, Wang C, Western D, Timsina J, Mangetti Goncalves T, Do AN, Sung YJ, Zhao G, Morris JC, Moulder K, Holtzman DM, Bateman RJ, Karch C, Hassenstab J, Xiong C, Schindler SE, Balls-Berry JJ, Benzinger TLS, Perrin RJ, Denny A, Snider BJ, Stark SL, Ibanez L, Cruchaga C. Fernandez MV, et al. Among authors: sung yj. Sci Data. 2024 Jul 12;11(1):768. doi: 10.1038/s41597-024-03485-9. Sci Data. 2024. PMID: 38997326 Free PMC article.
A genetic and proteomic comparison of key AD biomarkers across tissues.
Marsh TW, Western D, Timsina J, Gorijala P, Yang C, Pastor P, Liu M, Morris JC, Bateman RJ, Schindler SE, Sung YJ; Dominantly Inherited Alzheimer Network; Cruchaga C. Marsh TW, et al. Among authors: sung yj. Alzheimers Dement. 2024 Sep;20(9):6423-6440. doi: 10.1002/alz.14139. Epub 2024 Jul 30. Alzheimers Dement. 2024. PMID: 39077866 Free PMC article.
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.
Shen Y, Timsina J, Heo G, Beric A, Ali M, Wang C, Yang C, Wang Y, Western D, Liu M, Gorijala P, Budde J, Do A, Liu H, Gordon B, Llibre-Guerra JJ, Joseph-Mathurin N, Perrin RJ, Maschi D, Wyss-Coray T, Pastor P, Renton AE, Surace EI, Johnson ECB, Levey AI, Alvarez I, Levin J, Ringman JM, Allegri RF, Seyfried N, Day GS, Wu Q, Fernández MV, Tarawneh R, McDade E, Morris JC, Bateman RJ, Goate A; Dominantly Inherited Alzheimer Network; Ibanez L, Sung YJ, Cruchaga C. Shen Y, et al. Among authors: sung yj. Cell. 2024 Oct 31;187(22):6309-6326.e15. doi: 10.1016/j.cell.2024.08.049. Epub 2024 Sep 26. Cell. 2024. PMID: 39332414 Free PMC article.
291 results