Tramontano E - Search Results

1

Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach.

Ambrosio FA, Costa G, Romeo I, Esposito F, Alkhatib M, Salpini R, Svicher V, Corona A, Malune P, Tramontano E, Ceccherini-Silberstein F, Alcaro S, Artese A. Ambrosio FA, et al. Among authors: tramontano e. J Chem Inf Model. 2023 Jun 12;63(11):3601-3613. doi: 10.1021/acs.jcim.3c00282. Epub 2023 May 25. J Chem Inf Model. 2023. PMID: 37227780

2

The S-layer Protein DR_2577 Binds Deinoxanthin and under Desiccation Conditions Protects against UV-Radiation in Deinococcus radiodurans.

Farci D, Slavov C, Tramontano E, Piano D. Farci D, et al. Among authors: tramontano e. Front Microbiol. 2016 Feb 16;7:155. doi: 10.3389/fmicb.2016.00155. eCollection 2016. Front Microbiol. 2016. PMID: 26909071 Free PMC article.

3

In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase.

Mellors JW, Dutschman GE, Im GJ, Tramontano E, Winkler SR, Cheng YC. Mellors JW, et al. Among authors: tramontano e. Mol Pharmacol. 1992 Mar;41(3):446-51. Mol Pharmacol. 1992. PMID: 1372083

4

Antitumor agents. 1. Synthesis, biological evaluation, and molecular modeling of 5H-pyrido[3,2-a]phenoxazin-5-one, a compound with potent antiproliferative activity.

Bolognese A, Correale G, Manfra M, Lavecchia A, Mazzoni O, Novellino E, Barone V, Pani A, Tramontano E, La Colla P, Murgioni C, Serra I, Setzu G, Loddo R. Bolognese A, et al. Among authors: tramontano e. J Med Chem. 2002 Nov 21;45(24):5205-16. doi: 10.1021/jm020913z. J Med Chem. 2002. PMID: 12431048

5

HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587.

Tramontano E, Cheng YC. Tramontano E, et al. Biochem Pharmacol. 1992 Mar 17;43(6):1371-6. doi: 10.1016/0006-2952(92)90515-k. Biochem Pharmacol. 1992. PMID: 1373283 Free article.

6

Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance.

Im GJ, Tramontano E, Gonzalez CJ, Cheng YC. Im GJ, et al. Among authors: tramontano e. Biochem Pharmacol. 1993 Dec 14;46(12):2307-13. doi: 10.1016/0006-2952(93)90622-4. Biochem Pharmacol. 1993. PMID: 7506027 Free article.

7

Anti-aids agents, 6. Salaspermic acid, an anti-HIV principle from Tripterygium wilfordii, and the structure-activity correlation with its related compounds.

Chen K, Shi Q, Kashiwada Y, Zhang DC, Hu CQ, Jin JQ, Nozaki H, Kilkuskie RE, Tramontano E, Cheng YC, et al. Chen K, et al. Among authors: tramontano e. J Nat Prod. 1992 Mar;55(3):340-6. doi: 10.1021/np50081a010. J Nat Prod. 1992. PMID: 1375626

8

A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150).

Mellors JW, Im GJ, Tramontano E, Winkler SR, Medina DJ, Dutschman GE, Bazmi HZ, Piras G, Gonzalez CJ, Cheng YC. Mellors JW, et al. Among authors: tramontano e. Mol Pharmacol. 1993 Jan;43(1):11-6. Mol Pharmacol. 1993. PMID: 7678690

9

Comprehensive Characterization of the Human Endogenous Retrovirus HERV-K(HML-6) Group: Overview of Structure, Phylogeny, and Contribution to the Human Genome.

Pisano MP, Grandi N, Cadeddu M, Blomberg J, Tramontano E. Pisano MP, et al. Among authors: tramontano e. J Virol. 2019 Jul 30;93(16):e00110-19. doi: 10.1128/JVI.00110-19. Print 2019 Aug 15. J Virol. 2019. PMID: 31167914 Free PMC article.

10

The use of a new in vitro reaction substrate reproducing both U3 and U5 regions of the HIV-1 3'-ends increases the correlation between the in vitro and in vivo effects of the HIV-1 integrase inhibitors.

Tramontano E, Onidi L, Esposito F, Badas R, La Colla P. Tramontano E, et al. Biochem Pharmacol. 2004 May 1;67(9):1751-61. doi: 10.1016/j.bcp.2004.01.015. Biochem Pharmacol. 2004. PMID: 15081874

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