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Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis.
Kostel Bal S, Giuliani S, Block J, Repiscak P, Hafemeister C, Shahin T, Kasap N, Ransmayr B, Miao Y, van de Wetering C, Frohne A, Jimenez Heredia R, Schuster M, Zoghi S, Hertlein V, Thian M, Bykov A, Babayeva R, Bilgic Eltan S, Karakoc-Aydiner E, Shaw LE, Chowdhury I, Varjosalo M, Argüello RJ, Farlik M, Ozen A, Serfling E, Dupré L, Bock C, Halbritter F, Hannich JT, Castanon I, Kraakman MJ, Baris S, Boztug K. Kostel Bal S, et al. Among authors: varjosalo m. Blood. 2023 Aug 31;142(9):827-845. doi: 10.1182/blood.2022018303. Blood. 2023. PMID: 37249233 Free article.
Analyzing Protein Interactions by MAC-Tag Approaches.
Liu X, Salokas K, Keskitalo S, Martínez-Botía P, Varjosalo M. Liu X, et al. Among authors: varjosalo m. Methods Mol Biol. 2023;2690:281-297. doi: 10.1007/978-1-0716-3327-4_24. Methods Mol Biol. 2023. PMID: 37450155
Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
Turunen M, Spaeth JM, Keskitalo S, Park MJ, Kivioja T, Clark AD, Mäkinen N, Gao F, Palin K, Nurkkala H, Vähärautio A, Aavikko M, Kämpjärvi K, Vahteristo P, Kim CA, Aaltonen LA, Varjosalo M, Taipale J, Boyer TG. Turunen M, et al. Among authors: varjosalo m. Cell Rep. 2014 May 8;7(3):654-60. doi: 10.1016/j.celrep.2014.03.047. Epub 2014 Apr 18. Cell Rep. 2014. PMID: 24746821 Free PMC article.
The protein interaction landscape of the human CMGC kinase group.
Varjosalo M, Keskitalo S, Van Drogen A, Nurkkala H, Vichalkovski A, Aebersold R, Gstaiger M. Varjosalo M, et al. Cell Rep. 2013 Apr 25;3(4):1306-20. doi: 10.1016/j.celrep.2013.03.027. Epub 2013 Apr 18. Cell Rep. 2013. PMID: 23602568 Free article.
High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils.
Aaltonen N, Singha PK, Jakupović H, Wirth T, Samaranayake H, Pasonen-Seppänen S, Rilla K, Varjosalo M, Edgington-Mitchell LE, Kasperkiewicz P, Drag M, Kälvälä S, Moisio E, Savinainen JR, Laitinen JT. Aaltonen N, et al. Among authors: varjosalo m. Biol Proced Online. 2020 Mar 15;22:6. doi: 10.1186/s12575-020-00118-4. eCollection 2020. Biol Proced Online. 2020. PMID: 32190011 Free PMC article.
Increased intraocular pressure alters the cellular distribution of HuR protein in retinal ganglion cells - A possible sign of endogenous neuroprotection failure.
Smedowski A, Liu X, Podracka L, Akhtar S, Trzeciecka A, Pietrucha-Dutczak M, Lewin-Kowalik J, Urtti A, Ruponen M, Kaarniranta K, Varjosalo M, Amadio M. Smedowski A, et al. Among authors: varjosalo m. Biochim Biophys Acta Mol Basis Dis. 2018 Jan;1864(1):296-306. doi: 10.1016/j.bbadis.2017.10.030. Epub 2017 Oct 28. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29107807 Free article.
The comprehensive SARS-CoV-2 'hijackome' knowledge base.
Huuskonen S, Liu X, Pöhner I, Redchuk T, Salokas K, Lundberg R, Maljanen S, Belik M, Reinholm A, Kolehmainen P, Tuhkala A, Tripathi G, Laine P, Belanov S, Auvinen P, Vartiainen M, Keskitalo S, Österlund P, Laine L, Poso A, Julkunen I, Kakkola L, Varjosalo M. Huuskonen S, et al. Among authors: varjosalo m. Cell Discov. 2024 Dec 9;10(1):125. doi: 10.1038/s41421-024-00748-y. Cell Discov. 2024. PMID: 39653747 Free PMC article.
164 results