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In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain.
Yan X, Siméon FG, Liow JS, Morse CL, Montero Santamaria JA, Jenkins M, Manly LS, Van Buskirk M, Zoghbi SS, Pike VW, Innis RB, Zanotti-Fregonara P. Yan X, et al. Among authors: zanotti fregonara p. Eur J Nucl Med Mol Imaging. 2023 Aug;50(10):2962-2970. doi: 10.1007/s00259-023-06270-9. Epub 2023 May 30. Eur J Nucl Med Mol Imaging. 2023. PMID: 37249618 Free PMC article.
Evaluation in vitro and in animals of a new 11C-labeled PET radioligand for metabotropic glutamate receptors 1 in brain.
Zanotti-Fregonara P, Barth VN, Liow JS, Zoghbi SS, Clark DT, Rhoads E, Siuda E, Heinz BA, Nisenbaum E, Dressman B, Joshi E, Luffer-Atlas D, Fisher MJ, Masters JJ, Goebl N, Kuklish SL, Morse C, Tauscher J, Pike VW, Innis RB. Zanotti-Fregonara P, et al. Eur J Nucl Med Mol Imaging. 2013 Jan;40(2):245-53. doi: 10.1007/s00259-012-2269-7. Epub 2012 Nov 8. Eur J Nucl Med Mol Imaging. 2013. PMID: 23135321 Free PMC article.
The PET Radioligand 18F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain.
Zanotti-Fregonara P, Xu R, Zoghbi SS, Liow JS, Fujita M, Veronese M, Gladding RL, Rallis-Frutos D, Hong J, Pike VW, Innis RB. Zanotti-Fregonara P, et al. J Nucl Med. 2016 Feb;57(2):242-7. doi: 10.2967/jnumed.115.162461. Epub 2015 Oct 29. J Nucl Med. 2016. PMID: 26514176 Free PMC article. Clinical Trial.
Evaluation of a PET Radioligand to Image O-GlcNAcase in Brain and Periphery of Rhesus Monkey and Knock-Out Mouse.
Paul S, Haskali MB, Liow JS, Zoghbi SS, Barth VN, Kolodrubetz MC, Bond MR, Morse CL, Gladding RL, Frankland MP, Kant N, Slieker L, Shcherbinin S, Nuthall HN, Zanotti-Fregonara P, Hanover JA, Jesudason C, Pike VW, Innis RB. Paul S, et al. J Nucl Med. 2019 Jan;60(1):129-134. doi: 10.2967/jnumed.118.213231. Epub 2018 Sep 13. J Nucl Med. 2019. PMID: 30213846 Free PMC article.
[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain.
Yan X, Telu S, Dick RM, Liow JS, Zanotti-Fregonara P, Morse CL, Manly LS, Gladding RL, Shrestha S, Lerchner W, Nagai Y, Minamimoto T, Zoghbi SS, Innis RB, Pike VW, Richmond BJ, Eldridge MA. Yan X, et al. J Cereb Blood Flow Metab. 2021 Oct;41(10):2571-2582. doi: 10.1177/0271678X211007949. Epub 2021 Apr 14. J Cereb Blood Flow Metab. 2021. PMID: 33853405 Free PMC article.
First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B.
Wakabayashi Y, Stenkrona P, Arakawa R, Yan X, Van Buskirk MG, Jenkins MD, Santamaria JAM, Maresca KP, Takano A, Liow JS, Chappie TA, Varrone A, Nag S, Zhang L, Hughes ZA, Schmidt CJ, Doran SD, Mannes A, Zanotti-Fregonara P, Ooms M, Morse CL, Zoghbi SS, Halldin C, Pike VW, Innis RB. Wakabayashi Y, et al. J Nucl Med. 2022 Dec;63(12):1919-1924. doi: 10.2967/jnumed.122.263838. Epub 2022 Jun 30. J Nucl Med. 2022. PMID: 35772961 Free PMC article.
Kinetic analysis in human brain of [11C](R)-rolipram, a positron emission tomographic radioligand to image phosphodiesterase 4: a retest study and use of an image-derived input function.
Zanotti-Fregonara P, Zoghbi SS, Liow JS, Luong E, Boellaard R, Gladding RL, Pike VW, Innis RB, Fujita M. Zanotti-Fregonara P, et al. Neuroimage. 2011 Feb 1;54(3):1903-9. doi: 10.1016/j.neuroimage.2010.10.064. Epub 2010 Oct 26. Neuroimage. 2011. PMID: 21034834 Free PMC article.
134 results