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An improved SNAP-ADAR tool enables efficient RNA base editing to interfere with post-translational protein modification.
Kiran Kumar KD, Singh S, Schmelzle SM, Vogel P, Fruhner C, Hanswillemenke A, Brun A, Wettengel J, Füll Y, Funk L, Mast V, Botsch JJ, Reautschnig P, Li JB, Stafforst T. Kiran Kumar KD, et al. Among authors: stafforst t. Nat Commun. 2024 Aug 5;15(1):6615. doi: 10.1038/s41467-024-50395-w. Nat Commun. 2024. PMID: 39103360 Free PMC article.
Precise in vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA.
Reautschnig P, Fruhner C, Wahn N, Wiegand CP, Kragness S, Yung JF, Hofacker DT, Fisk J, Eidelman M, Waffenschmidt N, Feige M, Pfeiffer LS, Schulz AE, Füll Y, Levanon EY, Mandel G, Stafforst T. Reautschnig P, et al. Among authors: stafforst t. Nat Biotechnol. 2024 Jul 12. doi: 10.1038/s41587-024-02313-0. Online ahead of print. Nat Biotechnol. 2024. PMID: 38997581
Profiling the interactome of oligonucleotide drugs by proximity biotinylation.
Hanswillemenke A, Hofacker DT, Sorgenfrei M, Fruhner C, Franz-Wachtel M, Schwarzer D, Maček B, Stafforst T. Hanswillemenke A, et al. Among authors: stafforst t. Nat Chem Biol. 2024 May;20(5):555-565. doi: 10.1038/s41589-023-01530-z. Epub 2024 Jan 17. Nat Chem Biol. 2024. PMID: 38233583 Free PMC article.
Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications.
Helm M, Bohnsack MT, Carell T, Dalpke A, Entian KD, Ehrenhofer-Murray A, Ficner R, Hammann C, Höbartner C, Jäschke A, Jeltsch A, Kaiser S, Klassen R, Leidel SA, Marx A, Mörl M, Meier JC, Meister G, Rentmeister A, Rodnina M, Roignant JY, Schaffrath R, Stadler P, Stafforst T. Helm M, et al. Among authors: stafforst t. ACS Chem Biol. 2023 Dec 15;18(12):2441-2449. doi: 10.1021/acschembio.3c00586. Epub 2023 Nov 14. ACS Chem Biol. 2023. PMID: 37962075 Review.
Precise and efficient C-to-U RNA base editing with SNAP-CDAR-S.
Latifi N, Mack AM, Tellioglu I, Di Giorgio S, Stafforst T. Latifi N, et al. Among authors: stafforst t. Nucleic Acids Res. 2023 Aug 25;51(15):e84. doi: 10.1093/nar/gkad598. Nucleic Acids Res. 2023. PMID: 37462074 Free PMC article.
ADAR1-mediated RNA editing promotes B cell lymphomagenesis.
Pecori R, Ren W, Pirmoradian M, Wang X, Liu D, Berglund M, Li W, Tasakis RN, Di Giorgio S, Ye X, Li X, Arnold A, Wüst S, Schneider M, Selvasaravanan KD, Fuell Y, Stafforst T, Amini RM, Sonnevi K, Enblad G, Sander B, Wahlin BE, Wu K, Zhang H, Helm D, Binder M, Papavasiliou FN, Pan-Hammarström Q. Pecori R, et al. Among authors: stafforst t. iScience. 2023 May 12;26(6):106864. doi: 10.1016/j.isci.2023.106864. eCollection 2023 Jun 16. iScience. 2023. PMID: 37255666 Free PMC article.
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