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Page 1
Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling.
Li M, Patel HV, Cognetta AB 3rd, Smith TC 2nd, Mallick I, Cavalier JF, Previti ML, Canaan S, Aldridge BB, Cravatt BF, Seeliger JC. Li M, et al. Among authors: smith tc 2nd. Cell Chem Biol. 2022 May 19;29(5):883-896.e5. doi: 10.1016/j.chembiol.2021.09.002. Epub 2021 Oct 1. Cell Chem Biol. 2022. PMID: 34599873 Free PMC article.
Borrelia peptidoglycan interacting Protein (BpiP) contributes to the fitness of Borrelia burgdorferi against host-derived factors and influences virulence in mouse models of Lyme disease.
Chen Y, Vargas SM, Smith TC 2nd, Karna SLR, MacMackin Ingle T, Wozniak KL, Wormley FL Jr, Seshu J. Chen Y, et al. Among authors: smith tc 2nd. PLoS Pathog. 2021 Apr 21;17(4):e1009535. doi: 10.1371/journal.ppat.1009535. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33882111 Free PMC article.
Morphological profiling of tubercle bacilli identifies drug pathways of action.
Smith TC 2nd, Pullen KM, Olson MC, McNellis ME, Richardson I, Hu S, Larkins-Ford J, Wang X, Freundlich JS, Ando DM, Aldridge BB. Smith TC 2nd, et al. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18744-18753. doi: 10.1073/pnas.2002738117. Epub 2020 Jul 17. Proc Natl Acad Sci U S A. 2020. PMID: 32680963 Free PMC article.
Targeting drugs for tuberculosis.
Smith TC 2nd, Aldridge BB. Smith TC 2nd, et al. Science. 2019 Jun 28;364(6447):1234-1235. doi: 10.1126/science.aay0211. Science. 2019. PMID: 31249047 No abstract available.
Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action.
Boot M, Commandeur S, Subudhi AK, Bahira M, Smith TC 2nd, Abdallah AM, van Gemert M, Lelièvre J, Ballell L, Aldridge BB, Pain A, Speer A, Bitter W. Boot M, et al. Among authors: smith tc 2nd. Antimicrob Agents Chemother. 2018 Jun 26;62(7):e00083-18. doi: 10.1128/AAC.00083-18. Print 2018 Jul. Antimicrob Agents Chemother. 2018. PMID: 29661879 Free PMC article.
12 results