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SMALL MOLECULE IMAGING AGENT FOR MUTANT KRAS G12C.
Koch PD, Quintana J, Ahmed M, Kohler RH, Weissleder R. Koch PD, et al. Adv Ther (Weinh). 2021 May;4(5):2000290. doi: 10.1002/adtp.202000290. Epub 2021 Mar 12. Adv Ther (Weinh). 2021. PMID: 33997272 Free PMC article.
Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells.
Pfirschke C, Zilionis R, Engblom C, Messemaker M, Zou AE, Rickelt S, Gort-Freitas NA, Lin Y, Bill R, Siwicki M, Gungabeesoon J, Sprachman MM, Marquard AN, Rodell CB, Cuccarese MF, Quintana J, Ahmed MS, Kohler RH, Savova V, Weissleder R, Klein AM, Pittet MJ. Pfirschke C, et al. Cancer Immunol Res. 2022 Jan;10(1):40-55. doi: 10.1158/2326-6066.CIR-21-0326. Epub 2021 Dec 1. Cancer Immunol Res. 2022. PMID: 34795032 Free PMC article.
Deciphering albumin-directed drug delivery by imaging.
Hu H, Quintana J, Weissleder R, Parangi S, Miller M. Hu H, et al. Adv Drug Deliv Rev. 2022 Jun;185:114237. doi: 10.1016/j.addr.2022.114237. Epub 2022 Mar 29. Adv Drug Deliv Rev. 2022. PMID: 35364124 Free PMC article. Review.
Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release.
Quintana JM, Arboleda D, Hu H, Scott E, Luthria G, Pai S, Parangi S, Weissleder R, Miller MA. Quintana JM, et al. Bioconjug Chem. 2022 Aug 17;33(8):1474-1484. doi: 10.1021/acs.bioconjchem.2c00174. Epub 2022 Jul 14. Bioconjug Chem. 2022. PMID: 35833631 Free PMC article.
Localized in vivo prodrug activation using radionuclides.
Quintana JM, Jiang F, Kang M, Valladolid Onecha V, Könik A, Qin L, Rodriguez VE, Hu H, Borges N, Khurana I, Banla LI, Le Fur M, Caravan P, Schuemann J, Bertolet A, Weissleder R, Miller MA, Ng TSC. Quintana JM, et al. bioRxiv [Preprint]. 2024 Aug 6:2024.08.02.606075. doi: 10.1101/2024.08.02.606075. bioRxiv. 2024. PMID: 39211146 Free PMC article. Preprint.
Scission-Enhanced Molecular Imaging (SEMI).
Quintana JM, Carlson JCT, Scott E, Ng TSC, Miller MA, Weissleder R. Quintana JM, et al. Bioconjug Chem. 2024 Sep 10;35(10):1543-52. doi: 10.1021/acs.bioconjchem.4c00337. Online ahead of print. Bioconjug Chem. 2024. PMID: 39255972
301 results