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Page 1
Meta-omics profiling of the gut-lung axis illuminates metabolic networks and host-microbial interactions associated with elevated lung elastance in a murine model of obese allergic asthma.
Heinrich VA, Uvalle C, Manni ML, Li K, Mullett SJ, Donepudi SR, Clader J, Fitch A, Ellgass M, Cechova V, Qin S, Holguin F, Freeman BA, Methé BA, Morris A, Gelhaus SL. Heinrich VA, et al. Among authors: cechova v. Front Microbiomes. 2023;2:1153691. doi: 10.3389/frmbi.2023.1153691. Epub 2023 May 5. Front Microbiomes. 2023. PMID: 37293566 Free PMC article.
Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma.
Manni ML, Heinrich VA, Buchan GJ, O'Brien JP, Uvalle C, Cechova V, Koudelka A, Ukani D, Rawas-Qalaji M, Oury TD, Hart R, Ellgass M, Mullett SJ, Fajt ML, Wenzel SE, Holguin F, Freeman BA, Wendell SG. Manni ML, et al. Among authors: cechova v. Sci Rep. 2021 Sep 7;11(1):17788. doi: 10.1038/s41598-021-96471-9. Sci Rep. 2021. PMID: 34493738 Free PMC article.
Fatty acid nitroalkene reversal of established lung fibrosis.
Koudelka A, Cechova V, Rojas M, Mitash N, Bondonese A, St Croix C, Ross MA, Freeman BA. Koudelka A, et al. Among authors: cechova v. Redox Biol. 2022 Apr;50:102226. doi: 10.1016/j.redox.2021.102226. Epub 2021 Dec 29. Redox Biol. 2022. PMID: 35150970 Free PMC article.
Neuroprotective actions of a fatty acid nitroalkene in Parkinson's disease.
Di Maio R, Keeney MT, Cechova V, Mortimer A, Sekandari A, Rowart P, Greenamyre JT, Freeman BA, Fazzari M. Di Maio R, et al. Among authors: cechova v. NPJ Parkinsons Dis. 2023 Apr 7;9(1):55. doi: 10.1038/s41531-023-00502-3. NPJ Parkinsons Dis. 2023. PMID: 37029127 Free PMC article.
Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling.
Koudelka A, Buchan GJ, Cechova V, O'Brien JP, Liu H, Woodcock SR, Mullett SJ, Zhang C, Freeman BA, Gelhaus SL. Koudelka A, et al. Among authors: cechova v. bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.579101. doi: 10.1101/2024.02.06.579101. bioRxiv. 2024. Update in: J Lipid Res. 2024 Nov 19;66(1):100705. doi: 10.1016/j.jlr.2024.100705 PMID: 38370667 Free PMC article. Updated. Preprint.