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In vitro to in vivo extrapolation to derive a metabolism factor for estimating the aggregate exposure to salicylic acid after dermal exposure of its esters.
Najjar A, Grégoire S, Nicol B, Natsch A, Golbamaki N, Boisleve F, Irizar A, Wall B, Swinscoe A, Masini-Etévé V, Selechnik D, Api AM, Griem P, Hewitt N, Cardamone E. Najjar A, et al. Arch Toxicol. 2024 Jul;98(7):2199-2211. doi: 10.1007/s00204-024-03749-8. Epub 2024 Apr 24. Arch Toxicol. 2024. PMID: 38658404 Free PMC article.
In vitro pharmacologic profiling aids systemic toxicity assessment of chemicals.
Burbank M, Kukic P, Ouedraogo G, Kenna JG, Hewitt NJ, Armstrong D, Otto-Bruc A, Ebmeyer J, Boettcher M, Willox I, Mahony C. Burbank M, et al. Among authors: hewitt nj. Toxicol Appl Pharmacol. 2024 Nov;492:117131. doi: 10.1016/j.taap.2024.117131. Epub 2024 Oct 20. Toxicol Appl Pharmacol. 2024. PMID: 39437896 Free article.
Next generation risk assessment: an ab initio case study to assess the systemic safety of the cosmetic ingredient, benzyl salicylate, after dermal exposure.
Ebmeyer J, Najjar A, Lange D, Boettcher M, Voß S, Brandmair K, Meinhardt J, Kuehnl J, Hewitt NJ, Krueger CT, Schepky A. Ebmeyer J, et al. Among authors: hewitt nj. Front Pharmacol. 2024 Mar 7;15:1345992. doi: 10.3389/fphar.2024.1345992. eCollection 2024. Front Pharmacol. 2024. PMID: 38515841 Free PMC article.
86 results