Freedman NJ - Search Results

1

Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation.

Zhang L, Wu JH, Jean-Charles PY, Murali P, Zhang W, Jazic A, Kaur S, Nepliouev I, Stiber JA, Snow K, Freedman NJ, Shenoy SK. Zhang L, et al. Among authors: freedman nj. J Biol Chem. 2023 Jul;299(7):104911. doi: 10.1016/j.jbc.2023.104911. Epub 2023 Jun 11. J Biol Chem. 2023. PMID: 37311534 Free PMC article.

2

Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.

Jean-Charles PY, Zhang L, Wu JH, Han SO, Brian L, Freedman NJ, Shenoy SK. Jean-Charles PY, et al. Among authors: freedman nj. J Biol Chem. 2016 Apr 1;291(14):7450-64. doi: 10.1074/jbc.M115.687129. Epub 2016 Feb 2. J Biol Chem. 2016. PMID: 26839314 Free PMC article.

3

Regulation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-5 in vascular smooth muscle cells involves the phosphatase Shp2.

Wu JH, Goswami R, Cai X, Exum ST, Huang X, Zhang L, Brian L, Premont RT, Peppel K, Freedman NJ. Wu JH, et al. Among authors: freedman nj. J Biol Chem. 2006 Dec 8;281(49):37758-72. doi: 10.1074/jbc.M605756200. Epub 2006 Oct 3. J Biol Chem. 2006. PMID: 17018529 Free article.

4

USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis.

Jean-Charles PY, Wu JH, Zhang L, Kaur S, Nepliouev I, Stiber JA, Brian L, Qi R, Wertman V, Shenoy SK, Freedman NJ. Jean-Charles PY, et al. Among authors: freedman nj. Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2295-2305. doi: 10.1161/ATVBAHA.118.311071. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354204 Free PMC article.

5

Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor.

Shenoy SK, Xiao K, Venkataramanan V, Snyder PM, Freedman NJ, Weissman AM. Shenoy SK, et al. Among authors: freedman nj. J Biol Chem. 2008 Aug 8;283(32):22166-76. doi: 10.1074/jbc.M709668200. Epub 2008 Jun 10. J Biol Chem. 2008. PMID: 18544533 Free PMC article.

6

Regulation of inflammation by β-arrestins: Not just receptor tales.

Freedman NJ, Shenoy SK. Freedman NJ, et al. Cell Signal. 2018 Jan;41:41-45. doi: 10.1016/j.cellsig.2017.02.008. Epub 2017 Feb 9. Cell Signal. 2018. PMID: 28189586 Free PMC article. Review.

7

Drebrin attenuates atherosclerosis by limiting smooth muscle cell transdifferentiation.

Wu JH, Zhang L, Nepliouev I, Brian L, Huang T, Snow KP, Schickling BM, Hauser ER, Miller FJ, Freedman NJ, Stiber JA. Wu JH, et al. Among authors: freedman nj. Cardiovasc Res. 2022 Feb 21;118(3):772-784. doi: 10.1093/cvr/cvab156. Cardiovasc Res. 2022. PMID: 33914863 Free PMC article.

8

Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor.

Hildreth KL, Wu JH, Barak LS, Exum ST, Kim LK, Peppel K, Freedman NJ. Hildreth KL, et al. Among authors: freedman nj. J Biol Chem. 2004 Oct 1;279(40):41775-82. doi: 10.1074/jbc.M403274200. Epub 2004 Jul 22. J Biol Chem. 2004. PMID: 15271984 Free article.

9

The platelet-derived growth factor receptor-beta phosphorylates and activates G protein-coupled receptor kinase-2. A mechanism for feedback inhibition.

Wu JH, Goswami R, Kim LK, Miller WE, Peppel K, Freedman NJ. Wu JH, et al. Among authors: freedman nj. J Biol Chem. 2005 Sep 2;280(35):31027-35. doi: 10.1074/jbc.M501473200. Epub 2005 Jul 1. J Biol Chem. 2005. PMID: 15994317 Free article.

10

The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia.

Stiber JA, Wu JH, Zhang L, Nepliouev I, Zhang ZS, Bryson VG, Brian L, Bentley RC, Gordon-Weeks PR, Rosenberg PB, Freedman NJ. Stiber JA, et al. Among authors: freedman nj. Arterioscler Thromb Vasc Biol. 2016 May;36(5):984-93. doi: 10.1161/ATVBAHA.115.306140. Epub 2016 Mar 24. Arterioscler Thromb Vasc Biol. 2016. PMID: 27013612 Free PMC article.

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