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Page 1
Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires.
Philippon C, Tao S, Clement D, Haroun-Izquierdo A, Kichula KM, Netskar H, Brandt L, Oei VS, Kanaya M, Lanuza PM, Schaffer M, Goodridge JP, Horowitz A, Zhu F, Hammer Q, Sohlberg E, Majhi RK, Kveberg L, Önfelt B, Norman PJ, Malmberg KJ. Philippon C, et al. Among authors: hammer q. Blood Adv. 2023 Aug 22;7(16):4492-4504. doi: 10.1182/bloodadvances.2023009827. Blood Adv. 2023. PMID: 37327114 Free PMC article.
Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans.
Liu LL, Landskron J, Ask EH, Enqvist M, Sohlberg E, Traherne JA, Hammer Q, Goodridge JP, Larsson S, Jayaraman J, Oei VYS, Schaffer M, Taskén K, Ljunggren HG, Romagnani C, Trowsdale J, Malmberg KJ, Béziat V. Liu LL, et al. Among authors: hammer q. Cell Rep. 2016 May 3;15(5):1088-1099. doi: 10.1016/j.celrep.2016.04.005. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117418 Free PMC article.
Remodeling of secretory lysosomes during education tunes functional potential in NK cells.
Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ. Goodridge JP, et al. Among authors: hammer q. Nat Commun. 2019 Jan 31;10(1):514. doi: 10.1038/s41467-019-08384-x. Nat Commun. 2019. PMID: 30705279 Free PMC article.
Natural killer cell immunotypes related to COVID-19 disease severity.
Maucourant C, Filipovic I, Ponzetta A, Aleman S, Cornillet M, Hertwig L, Strunz B, Lentini A, Reinius B, Brownlie D, Cuapio A, Ask EH, Hull RM, Haroun-Izquierdo A, Schaffer M, Klingström J, Folkesson E, Buggert M, Sandberg JK, Eriksson LI, Rooyackers O, Ljunggren HG, Malmberg KJ, Michaëlsson J, Marquardt N, Hammer Q, Strålin K, Björkström NK; Karolinska COVID-19 Study Group. Maucourant C, et al. Among authors: hammer q. Sci Immunol. 2020 Aug 21;5(50):eabd6832. doi: 10.1126/sciimmunol.abd6832. Sci Immunol. 2020. PMID: 32826343 Free PMC article.
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells.
Hammer Q, Dunst J, Christ W, Picarazzi F, Wendorff M, Momayyezi P, Huhn O, Netskar HK, Maleki KT, García M, Sekine T, Sohlberg E, Azzimato V, Aouadi M; Karolinska COVID-19 Study Group; Severe COVID-19 GWAS Group; Degenhardt F, Franke A, Spallotta F, Mori M, Michaëlsson J, Björkström NK, Rückert T, Romagnani C, Horowitz A, Klingström J, Ljunggren HG, Malmberg KJ. Hammer Q, et al. Cell Rep. 2022 Mar 8;38(10):110503. doi: 10.1016/j.celrep.2022.110503. Epub 2022 Feb 21. Cell Rep. 2022. PMID: 35235832 Free PMC article.
An optimized platform for efficient siRNA delivery into human NK cells.
Palacios D, Momayyezi P, Huhn O, Ask EH, Dunst J, Malmberg KJ, Hammer Q. Palacios D, et al. Among authors: hammer q. Eur J Immunol. 2022 Jul;52(7):1190-1193. doi: 10.1002/eji.202149710. Epub 2022 Apr 22. Eur J Immunol. 2022. PMID: 35416292 Free PMC article.
Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia.
Haroun-Izquierdo A, Vincenti M, Netskar H, van Ooijen H, Zhang B, Bendzick L, Kanaya M, Momayyezi P, Li S, Wiiger MT, Hoel HJ, Krokeide SZ, Kremer V, Tjonnfjord G, Berggren S, Wikström K, Blomberg P, Alici E, Felices M, Önfelt B, Höglund P, Valamehr B, Ljunggren HG, Björklund A, Hammer Q, Kveberg L, Cichocki F, Miller JS, Malmberg KJ, Sohlberg E. Haroun-Izquierdo A, et al. Among authors: hammer q. J Immunother Cancer. 2022 Nov;10(11):e005577. doi: 10.1136/jitc-2022-005577. J Immunother Cancer. 2022. PMID: 36319065 Free PMC article.
31 results