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4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses.
Garzan A, Ahmed SK, Haese NN, Sulgey G, Medica S, Smith JL, Zhang S, Ahmad F, Karyakarte S, Rasmussen L, DeFilippis V, Tekwani B, Bostwick R, Suto MJ, Hirsch AJ, Morrison TE, Heise MT, Augelli-Szafran CE, Streblow DN, Pathak AK, Moukha-Chafiq O. Garzan A, et al. J Med Chem. 2024 Dec 12;67(23):20858-20878. doi: 10.1021/acs.jmedchem.4c01073. Epub 2024 Dec 2. J Med Chem. 2024. PMID: 39621435
N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase.
Coluccino G, Negro A, Filippi A, Bean C, Muraca VP, Gissi C, Canetti D, Mimmi MC, Zamprogno E, Ciscato F, Acquasaliente L, De Filippis V, Comelli M, Carraro M, Rasola A, Gerle C, Bernardi P, Corazza A, Lippe G. Coluccino G, et al. Among authors: de filippis v. Commun Biol. 2024 Nov 11;7(1):1486. doi: 10.1038/s42003-024-07172-8. Commun Biol. 2024. PMID: 39528709 Free PMC article.
Mayaro virus pathogenesis and immunity in rhesus macaques.
Weber WC, Labriola CS, Kreklywich CN, Ray K, Haese NN, Andoh TF, Denton M, Medica S, Streblow MM, Smith PP, Mizuno N, Frias N, Fisher MB, Barber-Axthelm AM, Chun K, Uttke S, Whitcomb D, DeFilippis V, Rakshe S, Fei SS, Axthelm MK, Smedley JV, Streblow DN. Weber WC, et al. PLoS Negl Trop Dis. 2023 Nov 20;17(11):e0011742. doi: 10.1371/journal.pntd.0011742. eCollection 2023 Nov. PLoS Negl Trop Dis. 2023. PMID: 37983245 Free PMC article.
A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue.
Mazzocato Y, Perin S, Morales-Sanfrutos J, Romanyuk Z, Pluda S, Acquasaliente L, Borsato G, De Filippis V, Scarso A, Angelini A. Mazzocato Y, et al. Among authors: de filippis v. Bioorg Med Chem. 2023 Nov 15;95:117499. doi: 10.1016/j.bmc.2023.117499. Epub 2023 Oct 12. Bioorg Med Chem. 2023. PMID: 37879145 Free article.
216 results