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Plasma neurofilament light chain concentrations are elevated in youth-onset type 2 diabetes and associated with neuropathy.
Fridman V, Sillau S, Ritchie A, Bockhorst J, Coughlan C, Araya P, Espinosa JM, Smith K, Lange EM, Lange LA, Ghormli LE, Drews KL, Zeitler P, Reusch JEB. Fridman V, et al. Among authors: coughlan c. J Peripher Nerv Syst. 2023 Sep;28(3):460-470. doi: 10.1111/jns.12575. Epub 2023 Aug 7. J Peripher Nerv Syst. 2023. PMID: 37341347 Free PMC article.
IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome.
Araya P, Kinning KT, Coughlan C, Smith KP, Granrath RE, Enriquez-Estrada BA, Worek K, Sullivan KD, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Galbraith MD, Potter H, Espinosa JM. Araya P, et al. Among authors: coughlan c. Cell Rep. 2022 Dec 27;41(13):111883. doi: 10.1016/j.celrep.2022.111883. Cell Rep. 2022. PMID: 36577365 Free PMC article.
Neuron loss in the brain starts in childhood, increases exponentially with age and is halted by GM-CSF treatment in Alzheimer's disease.
Sillau SH, Coughlan C, Ahmed MM, Nair K, Araya P, Galbraith MD, Bettcher BM, Espinosa JM, Chial HJ, Epperson N, Boyd TD, Potter H. Sillau SH, et al. Among authors: coughlan c. medRxiv [Preprint]. 2024 Jul 15:2024.07.14.24310223. doi: 10.1101/2024.07.14.24310223. medRxiv. 2024. PMID: 39072024 Free PMC article. Preprint.
Biomarkers of Neurodegeneration and Alzheimer's Disease Neuropathology in Adolescents and Young Adults with Youth-Onset Type 1 or Type 2 Diabetes: A Proof-of-Concept Study.
Shapiro ALB, Coughlan C, Bettcher BM, Pauley ME, Kim J, Bjornstad P, Rajic B, Truong J, Bell C, Choi YJ, Walker KA, Potter H, Liese AD, Dabelea D, Whitlow CT. Shapiro ALB, et al. Among authors: coughlan c. Endocrines. 2024 Jun;5(2):197-213. doi: 10.3390/endocrines5020014. Epub 2024 May 6. Endocrines. 2024. PMID: 38764894 Free PMC article.
Rapid Activation of Neuroinflammation in Stroke: Plasma and Extracellular Vesicles Obtained on a Mobile Stroke Unit.
Kowalski RG, Ledreux A, Violette JE, Neumann RT, Ornelas D, Yu X, Griffiths SG, Lewis S, Nash P, Monte AA, Coughlan CM, Deighan C, Grotta JC, Jones WJ, Graner MW. Kowalski RG, et al. Among authors: coughlan cm. Stroke. 2023 Mar;54(3):e52-e57. doi: 10.1161/STROKEAHA.122.041422. Epub 2023 Feb 2. Stroke. 2023. PMID: 36727508 Free PMC article.
Synergistic effects of GFAP and Aβ42: Implications for white matter integrity and verbal memory across the cognitive spectrum.
Bettcher BM, Lopez Paniagua D, Wang Y, McConnell BV, Coughlan C, Carlisle TC, Thaker AA, Lippitt W, Filley CM, Pelak VS, Shapiro ALB, Heffernan KS, Potter H, Solano A, Boyd J, Carlson NE. Bettcher BM, et al. Among authors: coughlan c. Brain Behav Immun Health. 2024 Aug 3;40:100834. doi: 10.1016/j.bbih.2024.100834. eCollection 2024 Oct. Brain Behav Immun Health. 2024. PMID: 39206431 Free PMC article.
Extracellular Vesicles from a Novel Chordoma Cell Line, ARF-8, Promote Tumorigenic Microenvironmental Changes When Incubated with the Parental Cells and with Human Osteoblasts.
Nguyen KN, Graner AN, Fringuello AR, Zizzo Z, Valenzuela L, Anyanwu K, Lillehei KO, Youssef AS, Guzman S, Coughlan C, Graner MW. Nguyen KN, et al. Among authors: coughlan c. Int J Mol Sci. 2024 Nov 27;25(23):12731. doi: 10.3390/ijms252312731. Int J Mol Sci. 2024. PMID: 39684443 Free PMC article.
Astrogliosis, neuritic microstructure, and sex effects: GFAP is an indicator of neuritic orientation in women.
Thaker AA, McConnell BV, Rogers DM, Carlson NE, Coughlan C, Jensen AM, Lopez-Paniagua D, Holden SK, Pressman PS, Pelak VS, Filley CM, Potter H, Solano DA, Heffernan KS, Bettcher BM. Thaker AA, et al. Among authors: coughlan c. Brain Behav Immun. 2023 Oct;113:124-135. doi: 10.1016/j.bbi.2023.06.026. Epub 2023 Jun 30. Brain Behav Immun. 2023. PMID: 37394144 Free PMC article.
Differential Effects of Extracellular Vesicles from Two Different Glioblastomas on Normal Human Brain Cells.
Wang M, Graner AN, Knowles B, McRae C, Fringuello A, Paucek P, Gavrilovic M, Redwine M, Hanson C, Coughlan C, Grimaldo-Garcia S, Metzger B, Bolus V, Kopper TJ, Smith M, Zhou W, Lenz M, Abosch A, Ojemann S, Lillehei KO, Yu X, Graner MW. Wang M, et al. Among authors: coughlan c. Neurol Int. 2024 Nov 6;16(6):1355-1384. doi: 10.3390/neurolint16060103. Neurol Int. 2024. PMID: 39585062 Free PMC article.
142 results