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Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma.
Peat TJ, Gaikwad SM, Dubois W, Gyabaah-Kessie N, Zhang S, Gorjifard S, Phyo Z, Andres M, Hughitt VK, Simpson RM, Miller MA, Girvin AT, Taylor A, Williams D, D'Antonio N, Zhang Y, Rajagopalan A, Flietner E, Wilson K, Zhang X, Shinn P, Klumpp-Thomas C, McKnight C, Itkin Z, Chen L, Kazandijian D, Zhang J, Michalowski AM, Simmons JK, Keats J, Thomas CJ, Mock BA. Peat TJ, et al. Among authors: dubois w. Cancer Lett. 2023 Aug 1;568:216284. doi: 10.1016/j.canlet.2023.216284. Epub 2023 Jun 24. Cancer Lett. 2023. PMID: 37356470 Free PMC article.
3D chromatin architecture, BRD4, and Mediator have distinct roles in regulating genome-wide transcriptional bursting and gene network.
Trzaskoma P, Jung S, Pękowska A, Bohrer CH, Wang X, Naz F, Dell'Orso S, Dubois WD, Olivera A, Vartak SV, Zhao Y, Nayak S, Overmiller A, Morasso MI, Sartorelli V, Larson DR, Chow CC, Casellas R, O'Shea JJ. Trzaskoma P, et al. Among authors: dubois wd. Sci Adv. 2024 Aug 9;10(32):eadl4893. doi: 10.1126/sciadv.adl4893. Epub 2024 Aug 9. Sci Adv. 2024. PMID: 39121214 Free PMC article.
WDR26 and MTF2 are therapeutic targets in multiple myeloma.
Sun F, Cheng Y, Riordan JD, Dupuy A, Dubois W, Pisano M, Dong J, Mock B, Zhan F, Hari P, Janz S. Sun F, et al. Among authors: dubois w. J Hematol Oncol. 2021 Dec 7;14(1):203. doi: 10.1186/s13045-021-01217-9. J Hematol Oncol. 2021. PMID: 34876184 Free PMC article.
Fatty acid oxidation is required for embryonic stem cell survival during metabolic stress.
Yan H, Malik N, Kim YI, He Y, Li M, Dubois W, Liu H, Peat TJ, Nguyen JT, Tseng YC, Ayaz G, Alzamzami W, Chan K, Andresson T, Tessarollo L, Mock BA, Lee MP, Huang J. Yan H, et al. Among authors: dubois w. EMBO Rep. 2021 Jun 4;22(6):e52122. doi: 10.15252/embr.202052122. Epub 2021 May 5. EMBO Rep. 2021. PMID: 33950553 Free PMC article.
Mouse tumor susceptibility genes identify drug combinations for multiple myeloma.
Zhang S, DuBois W, Zhang K, Simmons JK, Hughitt VK, Gorjifard S, Gaikwad S, Peat TJ, Mock BA. Zhang S, et al. Among authors: dubois w. J Cancer Metastasis Treat. 2020;6:21. doi: 10.20517/2394-4722.2020.40. Epub 2020 Jul 26. J Cancer Metastasis Treat. 2020. PMID: 32923678 Free PMC article.
95 results