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In retinal vein occlusion platelet response to thrombin is increased.
Leoncini G, Signorello MG, Segantin A, Giacobbe E, Armani U, Piana A, Camicione P. Leoncini G, et al. Among authors: signorello mg. Thromb Res. 2009 Dec;124(6):e48-55. doi: 10.1016/j.thromres.2009.07.010. Epub 2009 Aug 5. Thromb Res. 2009. PMID: 19660790
Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site.
Roma G, Di Braccio M, Grossi G, Piras D, Leoncini G, Bruzzese D, Signorello MG, Fossa P, Mosti L. Roma G, et al. Among authors: signorello mg. J Med Chem. 2007 Jun 14;50(12):2886-95. doi: 10.1021/jm0611511. Epub 2007 May 15. J Med Chem. 2007. PMID: 17500510
51 results