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Alzheimer and Parkinson diseases, frontotemporal lobar degeneration and amyotrophic lateral sclerosis overlapping neuropathology start in the first two decades of life in pollution exposed urbanites and brain ultrafine particulate matter and industrial nanoparticles, including Fe, Ti, Al, V, Ni, Hg, Co, Cu, Zn, Ag, Pt, Ce, La, Pr and W are key players. Metropolitan Mexico City health crisis is in progress.
Calderón-Garcidueñas L, Stommel EW, Torres-Jardón R, Hernández-Luna J, Aiello-Mora M, González-Maciel A, Reynoso-Robles R, Pérez-Guillé B, Silva-Pereyra HG, Tehuacanero-Cuapa S, Rodríguez-Gómez A, Lachmann I, Galaz-Montoya C, Doty RL, Roy A, Mukherjee PS. Calderón-Garcidueñas L, et al. Among authors: hernandez luna j. Front Hum Neurosci. 2024 Jan 12;17:1297467. doi: 10.3389/fnhum.2023.1297467. eCollection 2023. Front Hum Neurosci. 2024. PMID: 38283093 Free PMC article.
APOE Peripheral and Brain Impact: APOE4 Carriers Accelerate Their Alzheimer Continuum and Have a High Risk of Suicide in PM2.5 Polluted Cities.
Calderón-Garcidueñas L, Hernández-Luna J, Aiello-Mora M, Brito-Aguilar R, Evelson PA, Villarreal-Ríos R, Torres-Jardón R, Ayala A, Mukherjee PS. Calderón-Garcidueñas L, et al. Among authors: hernandez luna j. Biomolecules. 2023 May 31;13(6):927. doi: 10.3390/biom13060927. Biomolecules. 2023. PMID: 37371506 Free PMC article. Review.
Hemispheric Cortical, Cerebellar and Caudate Atrophy Associated to Cognitive Impairment in Metropolitan Mexico City Young Adults Exposed to Fine Particulate Matter Air Pollution.
Calderón-Garcidueñas L, Hernández-Luna J, Mukherjee PS, Styner M, Chávez-Franco DA, Luévano-Castro SC, Crespo-Cortés CN, Stommel EW, Torres-Jardón R. Calderón-Garcidueñas L, et al. Among authors: hernandez luna j. Toxics. 2022 Mar 25;10(4):156. doi: 10.3390/toxics10040156. Toxics. 2022. PMID: 35448417 Free PMC article.
Mild Cognitive Impairment and Dementia Involving Multiple Cognitive Domains in Mexican Urbanites.
Calderón-Garcidueñas L, Mukherjee PS, Kulesza RJ, Torres-Jardón R, Hernández-Luna J, Ávila-Cervantes R, Macías-Escobedo E, González-González O, González-Maciel A, García-Hernández K, Hernández-Castillo A, Villarreal-Ríos R; Research Universidad del Valle de México UVM Group. Calderón-Garcidueñas L, et al. Among authors: hernandez luna j. J Alzheimers Dis. 2019;68(3):1113-1123. doi: 10.3233/JAD-181208. J Alzheimers Dis. 2019. PMID: 30909241