Wen Z - Search Results

1

Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y₁₄ Receptor Antagonists.

Wen Z, Pramanik A, Lewicki SA, Jung YH, Gao ZG, Randle JCR, Cronin C, Chen Z, Giancotti LA, Whitehead GS, Liang BT, Breton S, Salvemini D, Cook DN, Jacobson KA. Wen Z, et al. J Med Chem. 2023 Jul 13;66(13):9076-9094. doi: 10.1021/acs.jmedchem.3c00664. Epub 2023 Jun 29. J Med Chem. 2023. PMID: 37382926 Free PMC article.

2

Exploration of Alternative Scaffolds for P2Y₁₄ Receptor Antagonists Containing a Biaryl Core.

Jung YH, Yu J, Wen Z, Salmaso V, Karcz TP, Phung NB, Chen Z, Duca S, Bennett JM, Dudas S, Salvemini D, Gao ZG, Cook DN, Jacobson KA. Jung YH, et al. Among authors: wen z. J Med Chem. 2020 Sep 10;63(17):9563-9589. doi: 10.1021/acs.jmedchem.0c00745. Epub 2020 Aug 6. J Med Chem. 2020. PMID: 32787142 Free PMC article.

3

Structure-Activity Relationship of Heterocyclic P2Y₁₄ Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres.

Jung YH, Salmaso V, Wen Z, Bennett JM, Phung NB, Lieberman DI, Gopinatth V, Randle JCR, Chen Z, Salvemini D, Karcz TP, Cook DN, Jacobson KA. Jung YH, et al. Among authors: wen z. J Med Chem. 2021 Apr 22;64(8):5099-5122. doi: 10.1021/acs.jmedchem.1c00164. Epub 2021 Mar 31. J Med Chem. 2021. PMID: 33787273 Free PMC article.

4

Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y₁₄R Antagonist.

Wen Z, Salmaso V, Jung YH, Phung NB, Gopinatth V, Shah Q, Patterson AT, Randle JCR, Chen Z, Salvemini D, Lieberman DI, Whitehead GS, Karcz TP, Cook DN, Jacobson KA. Wen Z, et al. J Med Chem. 2022 Feb 24;65(4):3434-3459. doi: 10.1021/acs.jmedchem.1c01964. Epub 2022 Feb 3. J Med Chem. 2022. PMID: 35113556 Free PMC article.

5

Dihydropyridines Potentiate ATP-Induced Currents Mediated by the Full-Length Human P2X5 Receptor.

Schiller IC, Jacobson KA, Wen Z, Malisetty A, Schmalzing G, Markwardt F. Schiller IC, et al. Among authors: wen z. Molecules. 2022 Mar 11;27(6):1846. doi: 10.3390/molecules27061846. Molecules. 2022. PMID: 35335209 Free PMC article.

6

Stereospecific antiseizure activity in mouse and rat epilepsy models by a pyridinium inhibitor of TNFα/NFκB signaling.

Pollard BS, Wen Z, Jacobson KA, Pollard JR. Pollard BS, et al. Among authors: wen z. Eur J Med Chem Rep. 2022 Dec;6:100065. doi: 10.1016/j.ejmcr.2022.100065. Epub 2022 Jun 8. Eur J Med Chem Rep. 2022. PMID: 36003949 Free PMC article.

7

Structure-Activity Relationship and Neuroprotective Activity of 1,5-Dihydro-2H-naphtho[1,2-b][1,4]diazepine-2,4(3H)-diones as P2X4 Receptor Antagonists.

Toti KS, Verma R, McGonnigle MJ, Gamiotea Turro D, Wen Z, Lewicki SA, Liang BT, Jacobson KA. Toti KS, et al. Among authors: wen z. J Med Chem. 2022 Oct 27;65(20):13967-13987. doi: 10.1021/acs.jmedchem.2c01197. Epub 2022 Sep 23. J Med Chem. 2022. PMID: 36150180 Free PMC article.

8

Effects of Purinergic Receptor Deletion or Pharmacologic Modulation on Pulmonary Inflammation in Mice.

Whitehead GS, Karcz TP, Tosh DK, Jung YH, Wen Z, Campbell RG, Gopinatth V, Gao ZG, Jacobson KA, Cook DN. Whitehead GS, et al. Among authors: wen z. ACS Pharmacol Transl Sci. 2022 Oct 5;5(10):973-984. doi: 10.1021/acsptsci.2c00128. eCollection 2022 Oct 14. ACS Pharmacol Transl Sci. 2022. PMID: 36268115 Free PMC article.

9

New paradigms in purinergic receptor ligand discovery.

Jacobson KA, Pradhan B, Wen Z, Pramanik A. Jacobson KA, et al. Among authors: wen z. Neuropharmacology. 2023 Jun 1;230:109503. doi: 10.1016/j.neuropharm.2023.109503. Epub 2023 Mar 13. Neuropharmacology. 2023. PMID: 36921890 Free PMC article. Review.

10

Corrigendum to "New paradigms in purinergic receptor ligand discovery" [Neuropharmacology 230 (2023) 109503].

Jacobson KA, Pradhan B, Wen Z, Pramanik A. Jacobson KA, et al. Among authors: wen z. Neuropharmacology. 2023 Dec 15;241:109731. doi: 10.1016/j.neuropharm.2023.109731. Epub 2023 Oct 7. Neuropharmacology. 2023. PMID: 37806912 Free PMC article. No abstract available.

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