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Ribosomal protein control of hematopoietic stem cell transformation through direct, non-canonical regulation of metabolism.
Harris B, Singh DK, Verma M, Fahl SP, Rhodes M, Sprinkle SR, Wang M, Zhang Y, Perrigoue J, Kessel R, Peri S, West J, Giricz O, Boultwood J, Pellagatti A, Ramesh KH, Montagna C, Pradhan K, Tyner JW, Kennedy BK, Holinstat M, Steidl U, Sykes S, Verma A, Wiest DL. Harris B, et al. Among authors: wiest dl. bioRxiv [Preprint]. 2023 Jun 1:2023.05.31.543132. doi: 10.1101/2023.05.31.543132. bioRxiv. 2023. PMID: 37398007 Free PMC article. Preprint.
Disruption of polyunsaturated fatty acid biosynthesis drives STING-dependent acute myeloid leukemia cell maturation and death.
Kanefsky J, Basse M, Sokei J, di Martino O, Valin L, Jaspers Y, Martinez E, Huhn J, Di Marcantonio D, Magee JA, Goldman AR, Tang HY, Ferraro F, Kemp S, Wiest DL, Sykes SM. Kanefsky J, et al. Among authors: wiest dl. J Biol Chem. 2024 May;300(5):107214. doi: 10.1016/j.jbc.2024.107214. Epub 2024 Mar 22. J Biol Chem. 2024. PMID: 38522521 Free PMC article.
TCF1 dosage determines cell fate during T cell development.
Verma A, Aylward B, Ma F, Sherman CA, Chopp L, Shinton S, Roy R, Fahl S, Contreras A, Koenitzer B, Awasthi P, Mazan-Mamczarz K, De S, Ollikainen N, Qiu X, Bosselut R, Sen R, Wiest DL, Sen JM. Verma A, et al. Among authors: wiest dl. Sci Adv. 2024 Nov 29;10(48):eado5982. doi: 10.1126/sciadv.ado5982. Epub 2024 Nov 27. Sci Adv. 2024. PMID: 39602533 Free PMC article.
Doubling down to make killer T cells.
Kappes D, Wiest DL. Kappes D, et al. Among authors: wiest dl. Nat Immunol. 2023 Sep;24(9):1407-1408. doi: 10.1038/s41590-023-01593-z. Nat Immunol. 2023. PMID: 37620604 No abstract available.
Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system.
Gao Y, Wang Y, Chauss D, Villarino AV, Link VM, Nagashima H, Spinner CA, Koparde VN, Bouladoux N, Abers MS, Break TJ, Chopp LB, Park JH, Zhu J, Wiest DL, Leonard WJ, Lionakis MS, O'Shea JJ, Afzali B, Belkaid Y, Lazarevic V. Gao Y, et al. Among authors: wiest dl. Nat Immunol. 2023 Aug;24(8):1331-1344. doi: 10.1038/s41590-023-01553-7. Epub 2023 Jul 13. Nat Immunol. 2023. PMID: 37443284 Free PMC article.
124 results