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Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity.
Ma L, Hostetler A, Morgan DM, Maiorino L, Sulkaj I, Whittaker CA, Neeser A, Pires IS, Yousefpour P, Gregory J, Qureshi K, Dye J, Abraham W, Suh H, Li N, Love JC, Irvine DJ. Ma L, et al. Among authors: whittaker ca. Cell. 2023 Jul 20;186(15):3148-3165.e20. doi: 10.1016/j.cell.2023.06.002. Epub 2023 Jul 5. Cell. 2023. PMID: 37413990 Free PMC article.
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.
Ramos A, Koch CE, Liu-Lupo Y, Hellinger RD, Kyung T, Abbott KL, Fröse J, Goulet D, Gordon KS, Eidell KP, Leclerc P, Whittaker CA, Larson RC, Muscato AJ, Yates KB, Dubrot J, Doench JG, Regev A, Vander Heiden MG, Maus MV, Manguso RT, Birnbaum ME, Hemann MT. Ramos A, et al. Among authors: whittaker ca. Nat Commun. 2023 Dec 5;14(1):8048. doi: 10.1038/s41467-023-43790-2. Nat Commun. 2023. PMID: 38052854 Free PMC article.
BMI1 is required for melanocyte stem cell maintenance and hair pigmentation.
Wilson MM, Danielian PS, Salus G, Ferretti R, Whittaker CA, Lees JA. Wilson MM, et al. Among authors: whittaker ca. Pigment Cell Melanoma Res. 2023 Sep;36(5):399-406. doi: 10.1111/pcmr.13088. Epub 2023 May 3. Pigment Cell Melanoma Res. 2023. PMID: 37132544 Free PMC article.
Short-term post-fast refeeding enhances intestinal stemness via polyamines.
Imada S, Khawaled S, Shin H, Meckelmann SW, Whittaker CA, Corrêa RO, Alquati C, Lu Y, Tie G, Pradhan D, Calibasi-Kocal G, Nascentes Melo LM, Allies G, Rösler J, Wittenhofer P, Krystkiewicz J, Schmitz OJ, Roper J, Vinolo MAR, Ricciardiello L, Lien EC, Vander Heiden MG, Shivdasani RA, Cheng CW, Tasdogan A, Yilmaz ÖH. Imada S, et al. Among authors: whittaker ca. Nature. 2024 Sep;633(8031):895-904. doi: 10.1038/s41586-024-07840-z. Epub 2024 Aug 21. Nature. 2024. PMID: 39169180
Targeted Degradation of CDK9 Potently Disrupts the MYC Transcriptional Network.
Toure MA, Motoyama K, Xiang Y, Urgiles J, Kabinger F, Koglin AS, Iyer RS, Gagnon K, Kumar A, Ojeda S, Harrison DA, Rees MG, Roth JA, Ott CJ, Schiavoni R, Whittaker CA, Levine SS, White FM, Calo E, Richters A, Koehler AN. Toure MA, et al. Among authors: whittaker ca. bioRxiv [Preprint]. 2024 May 15:2024.05.14.593352. doi: 10.1101/2024.05.14.593352. bioRxiv. 2024. PMID: 38952800 Free PMC article. Preprint.
86 results