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Novel strategies to assess cytokine release mediated by chimeric antigen receptor T cells based on the adverse outcome pathway concept.
Alb M, Reiche K, Rade M, Sewald K, Loskill P, Cipriano M, Maulana TI, van der Meer AD, Weener HJ, Clerbaux LA, Fogal B, Patel N, Adkins K, Lund E, Perkins E, Cooper C, van den Brulle J, Morgan H, Rubic-Schneider T, Ling H, DiPetrillo K, Moggs J, Köhl U, Hudecek M. Alb M, et al. Among authors: loskill p. J Immunotoxicol. 2024 Oct;21(sup1):S13-S28. doi: 10.1080/1547691X.2024.2345158. Epub 2024 Dec 10. J Immunotoxicol. 2024. PMID: 39655500 Free article. Review.
Opportunities for Microphysiological Systems in Toxicity Testing of New Drug Modalities.
Maulana TI, Wevers NR, Kristoforus T, Chandler M, Lanz HL, Joore J, Vulto P, Villenave R, Kustermann S, Loskill P, Bircsak KM. Maulana TI, et al. Among authors: loskill p. Annu Rev Pharmacol Toxicol. 2025 Jan;65(1):47-69. doi: 10.1146/annurev-pharmtox-061724-080621. Epub 2024 Dec 17. Annu Rev Pharmacol Toxicol. 2025. PMID: 39227343 Review.
Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility.
Pamies D, Ekert J, Zurich MG, Frey O, Werner S, Piergiovanni M, Freedman BS, Keong Teo AK, Erfurth H, Reyes DR, Loskill P, Candarlioglu P, Suter-Dick L, Wang S, Hartung T, Coecke S, Stacey GN, Wagegg BA, Dehne EM, Pistollato F, Leist M. Pamies D, et al. Among authors: loskill p. Stem Cell Reports. 2024 Jul 2;19(7):1041. doi: 10.1016/j.stemcr.2024.06.007. Online ahead of print. Stem Cell Reports. 2024. PMID: 38959889 Free PMC article. No abstract available.
Breast cancer-on-chip for patient-specific efficacy and safety testing of CAR-T cells.
Maulana TI, Teufel C, Cipriano M, Roosz J, Lazarevski L, van den Hil FE, Scheller L, Orlova V, Koch A, Hudecek M, Alb M, Loskill P. Maulana TI, et al. Among authors: loskill p. Cell Stem Cell. 2024 Jul 5;31(7):989-1002.e9. doi: 10.1016/j.stem.2024.04.018. Epub 2024 May 15. Cell Stem Cell. 2024. PMID: 38754430 Free article.
Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility.
Pamies D, Ekert J, Zurich MG, Frey O, Werner S, Piergiovanni M, Freedman BS, Keong Teo AK, Erfurth H, Reyes DR, Loskill P, Candarlioglu P, Suter-Dick L, Wang S, Hartung T, Coecke S, Stacey GN, Wagegg BA, Dehne EM, Pistollato F, Leist M. Pamies D, et al. Among authors: loskill p. Stem Cell Reports. 2024 May 14;19(5):604-617. doi: 10.1016/j.stemcr.2024.03.009. Epub 2024 Apr 25. Stem Cell Reports. 2024. PMID: 38670111 Free PMC article. Review.
70 results