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S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells.
Nagira Y, Nagira M, Nagai R, Nogami W, Hirata M, Ueyama A, Yoshida T, Yoshikawa M, Shinonome S, Yoshida H, Haruna M, Miwa H, Chatani N, Ohkura N, Wada H, Tanaka H. Nagira Y, et al. Among authors: wada h. Mol Cancer Ther. 2023 Sep 5;22(9):1063-1072. doi: 10.1158/1535-7163.MCT-22-0570. Mol Cancer Ther. 2023. PMID: 37420296 Free PMC article.
Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers.
Saito T, Nishikawa H, Wada H, Nagano Y, Sugiyama D, Atarashi K, Maeda Y, Hamaguchi M, Ohkura N, Sato E, Nagase H, Nishimura J, Yamamoto H, Takiguchi S, Tanoue T, Suda W, Morita H, Hattori M, Honda K, Mori M, Doki Y, Sakaguchi S. Saito T, et al. Among authors: wada h. Nat Med. 2016 Jun;22(6):679-84. doi: 10.1038/nm.4086. Epub 2016 Apr 25. Nat Med. 2016. PMID: 27111280
Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment.
Iwahori K, Shintani Y, Funaki S, Yamamoto Y, Matsumoto M, Yoshida T, Morimoto-Okazawa A, Kawashima A, Sato E, Gottschalk S, Okumura M, Kumanogoh A, Wada H. Iwahori K, et al. Among authors: wada h. Sci Rep. 2019 Feb 22;9(1):2636. doi: 10.1038/s41598-019-39345-5. Sci Rep. 2019. PMID: 30796310 Free PMC article.
Peri-operative monocyte count is a marker of poor prognosis in gastric cancer: increased monocytes are a characteristic of myeloid-derived suppressor cells.
Urakawa S, Yamasaki M, Goto K, Haruna M, Hirata M, Morimoto-Okazawa A, Kawashima A, Iwahori K, Makino T, Kurokawa Y, Yamada T, Mori M, Doki Y, Wada H. Urakawa S, et al. Among authors: wada h. Cancer Immunol Immunother. 2019 Aug;68(8):1341-1350. doi: 10.1007/s00262-019-02366-0. Epub 2019 Jul 19. Cancer Immunol Immunother. 2019. PMID: 31324947 Free PMC article.
Endogenous CXCL9 affects prognosis by regulating tumor-infiltrating natural killer cells in intrahepatic cholangiocarcinoma.
Fukuda Y, Asaoka T, Eguchi H, Yokota Y, Kubo M, Kinoshita M, Urakawa S, Iwagami Y, Tomimaru Y, Akita H, Noda T, Gotoh K, Kobayashi S, Hirata M, Wada H, Mori M, Doki Y. Fukuda Y, et al. Among authors: wada h. Cancer Sci. 2020 Feb;111(2):323-333. doi: 10.1111/cas.14267. Epub 2020 Jan 23. Cancer Sci. 2020. PMID: 31799781 Free PMC article.
Clinical importance of the expression of CD4+CD8+ T cells in renal cell carcinoma.
Nishida K, Kawashima A, Kanazawa T, Kidani Y, Yoshida T, Hirata M, Yamamoto K, Yamamoto Y, Sawada M, Kato R, Kato T, Hatano K, Ujike T, Fujita K, Uemura M, Morimoto-Okazawa A, Iwahori K, Yamasaki M, Ohkura N, Sakaguchi S, Nonomura N, Doki Y, Wada H. Nishida K, et al. Among authors: wada h. Int Immunol. 2020 May 8;32(5):347-357. doi: 10.1093/intimm/dxaa004. Int Immunol. 2020. PMID: 31950169
PD-1+ Tim3+ tumor-infiltrating CD8 T cells sustain the potential for IFN-γ production, but lose cytotoxic activity in ovarian cancer.
Sawada M, Goto K, Morimoto-Okazawa A, Haruna M, Yamamoto K, Yamamoto Y, Nakagawa S, Hiramatsu K, Matsuzaki S, Kobayashi E, Kawashima A, Hirata M, Iwahori K, Kimura T, Ueda Y, Kimura T, Wada H. Sawada M, et al. Among authors: wada h. Int Immunol. 2020 May 30;32(6):397-405. doi: 10.1093/intimm/dxaa010. Int Immunol. 2020. PMID: 32009163
Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer.
Haruna M, Hirata M, Iwahori K, Kanazawa T, Yamamoto Y, Goto K, Kawashima A, Morimoto-Okazawa A, Funaki S, Shintani Y, Kumanogoh A, Wada H. Haruna M, et al. Among authors: wada h. Biol Pharm Bull. 2020;43(3):399-403. doi: 10.1248/bpb.b19-00702. Biol Pharm Bull. 2020. PMID: 32115500 Free article.
Tumour grade significantly correlates with total dysfunction of tumour tissue-infiltrating lymphocytes in renal cell carcinoma.
Kawashima A, Kanazawa T, Kidani Y, Yoshida T, Hirata M, Nishida K, Nojima S, Yamamoto Y, Kato T, Hatano K, Ujike T, Nagahara A, Fujita K, Morimoto-Okazawa A, Iwahori K, Uemura M, Imamura R, Ohkura N, Morii E, Sakaguchi S, Wada H, Nonomura N. Kawashima A, et al. Among authors: wada h. Sci Rep. 2020 Apr 10;10(1):6220. doi: 10.1038/s41598-020-63060-1. Sci Rep. 2020. PMID: 32277125 Free PMC article.
4,026 results