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Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M4 mAChR.
Jörg M, van der Westhuizen ET, Lu Y, Christopher Choy KH, Shackleford DM, Khajehali E, Tobin AB, Thal DM, Capuano B, Christopoulos A, Valant C, Scammells PJ. Jörg M, et al. Among authors: capuano b. Eur J Med Chem. 2023 Oct 5;258:115588. doi: 10.1016/j.ejmech.2023.115588. Epub 2023 Jul 1. Eur J Med Chem. 2023. PMID: 37423123 Free PMC article.
Design strategies for bivalent ligands targeting GPCRs.
Shonberg J, Scammells PJ, Capuano B. Shonberg J, et al. Among authors: capuano b. ChemMedChem. 2011 Jun 6;6(6):963-74. doi: 10.1002/cmdc.201100101. Epub 2011 Apr 21. ChemMedChem. 2011. PMID: 21520422 Review.
75 results