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Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis.
Shiau C, Cao J, Gregory MT, Gong D, Yin X, Cho JW, Wang PL, Su J, Wang S, Reeves JW, Kim TK, Kim Y, Guo JA, Lester NA, Schurman N, Barth JL, Weissleder R, Jacks T, Qadan M, Hong TS, Wo JY, Roberts H, Beechem JM, Castillo CF, Mino-Kenudson M, Ting DT, Hemberg M, Hwang WL. Shiau C, et al. Among authors: hemberg m. bioRxiv [Preprint]. 2023 Jun 29:2023.06.28.546848. doi: 10.1101/2023.06.28.546848. bioRxiv. 2023. PMID: 37425692 Free PMC article. Preprint.
Integrative single-cell characterization of frugivory adaptations in the bat kidney and pancreas.
Gordon WE, Baek S, Nguyen HP, Kuo YM, Bradley R, Galazyuk A, Lee I, Ingala MR, Simmons NB, Schountz T, Cooper LN, Georgakopoulos-Soares I, Hemberg M, Ahituv N. Gordon WE, et al. Among authors: hemberg m. bioRxiv [Preprint]. 2023 Feb 13:2023.02.12.528204. doi: 10.1101/2023.02.12.528204. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 9;15(1):12. doi: 10.1038/s41467-023-44186-y PMID: 36824791 Free PMC article. Updated. Preprint.
MEA-NAP: A flexible network analysis pipeline for neuronal 2D and 3D organoid multielectrode recordings.
Sit TPH, Feord RC, Dunn AWE, Chabros J, Oluigbo D, Smith HH, Burn L, Chang E, Boschi A, Yuan Y, Gibbons GM, Khayat-Khoei M, De Angelis F, Hemberg E, Hemberg M, Lancaster MA, Lakatos A, Eglen SJ, Paulsen O, Mierau SB. Sit TPH, et al. Among authors: hemberg m. Cell Rep Methods. 2024 Nov 18;4(11):100901. doi: 10.1016/j.crmeth.2024.100901. Epub 2024 Nov 8. Cell Rep Methods. 2024. PMID: 39520988 Free PMC article.
Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment.
Shiau C, Cao J, Gong D, Gregory MT, Caldwell NJ, Yin X, Cho JW, Wang PL, Su J, Wang S, Reeves JW, Kim TK, Kim Y, Guo JA, Lester NA, Bae JW, Zhao R, Schurman N, Barth JL, Ganci ML, Weissleder R, Jacks T, Qadan M, Hong TS, Wo JY, Roberts H, Beechem JM, Castillo CF, Mino-Kenudson M, Ting DT, Hemberg M, Hwang WL. Shiau C, et al. Among authors: hemberg m. Nat Genet. 2024 Nov;56(11):2466-2478. doi: 10.1038/s41588-024-01890-9. Epub 2024 Sep 3. Nat Genet. 2024. PMID: 39227743
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.
Mertens RT, Misra A, Xiao P, Baek S, Rone JM, Mangani D, Sivanathan KN, Arojojoye AS, Awuah SG, Lee I, Shi GP, Petrova B, Brook JR, Anderson AC, Flavell RA, Kanarek N, Hemberg M, Nowarski R. Mertens RT, et al. Among authors: hemberg m. Immunity. 2024 Sep 10;57(9):2077-2094.e12. doi: 10.1016/j.immuni.2024.06.001. Epub 2024 Jun 20. Immunity. 2024. PMID: 38906145
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