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Page 1
Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation.
Yeh AC, Koyama M, Waltner OG, Minnie SA, Boiko JR, Shabaneh TB, Takahashi S, Zhang P, Ensbey KS, Schmidt CR, Legg SRW, Sekiguchi T, Nelson E, Bhise SS, Stevens AR, Goodpaster T, Chakka S, Furlan SN, Markey KA, Bleakley ME, Elson CO, Bradley PH, Hill GR. Yeh AC, et al. Among authors: legg srw. Immunity. 2024 Jul 9;57(7):1648-1664.e9. doi: 10.1016/j.immuni.2024.05.018. Epub 2024 Jun 13. Immunity. 2024. PMID: 38876098
TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies.
Minnie SA, Waltner OG, Zhang P, Takahashi S, Nemychenkov NS, Ensbey KS, Schmidt CR, Legg SRW, Comstock M, Boiko JR, Nelson E, Bhise SS, Wilkens AB, Koyama M, Dhodapkar MV, Chesi M, Riddell SR, Green DJ, Spencer A, Furlan SN, Hill GR. Minnie SA, et al. Among authors: legg srw. Sci Immunol. 2024 Apr 19;9(94):eadg1094. doi: 10.1126/sciimmunol.adg1094. Epub 2024 Apr 19. Sci Immunol. 2024. PMID: 38640253 Free PMC article.
Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation.
Bragg RM, Coffey SR, Cantle JP, Hu S, Singh S, Legg SRW, McHugh CA, Toor A, Zeitlin SO, Kwak S, Howland D, Vogt TF, Monga SP, Carroll JB. Bragg RM, et al. Among authors: legg srw. bioRxiv [Preprint]. 2023 Jun 26:2023.06.24.546334. doi: 10.1101/2023.06.24.546334. bioRxiv. 2023. Update in: Life Sci Alliance. 2023 Sep 8;6(11):e202302098. doi: 10.26508/lsa.202302098 PMID: 37425835 Free PMC article. Updated. Preprint.
Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.
Minnie SA, Waltner OG, Ensbey KS, Nemychenkov NS, Schmidt CR, Bhise SS, Legg SRW, Campoy G, Samson LD, Kuns RD, Zhou T, Huck JD, Vuckovic S, Zamora D, Yeh A, Spencer A, Koyama M, Markey KA, Lane SW, Boeckh M, Ring AM, Furlan SN, Hill GR. Minnie SA, et al. Among authors: legg srw. Sci Immunol. 2022 Oct 21;7(76):eabo3420. doi: 10.1126/sciimmunol.abo3420. Epub 2022 Oct 14. Sci Immunol. 2022. PMID: 36240285 Free PMC article.