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Page 1
Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis.
Blaser MC, Buffolo F, Halu A, Turner ME, Schlotter F, Higashi H, Pantano L, Clift CL, Saddic LA, Atkins SK, Rogers MA, Pham T, Vromman A, Shvartz E, Sukhova GK, Monticone S, Camussi G, Robson SC, Body SC, Muehlschlegel JD, Singh SA, Aikawa M, Aikawa E. Blaser MC, et al. Among authors: schlotter f. Circulation. 2023 Aug 22;148(8):661-678. doi: 10.1161/CIRCULATIONAHA.122.063402. Epub 2023 Jul 10. Circulation. 2023. PMID: 37427430 Free PMC article.
Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E. Schlotter F, et al. Circulation. 2018 Jul 24;138(4):377-393. doi: 10.1161/CIRCULATIONAHA.117.032291. Circulation. 2018. PMID: 29588317 Free PMC article.
18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images.
Creager MD, Hohl T, Hutcheson JD, Moss AJ, Schlotter F, Blaser MC, Park MA, Lee LH, Singh SA, Alcaide-Corral CJ, Tavares AAS, Newby DE, Kijewski MF, Aikawa M, Di Carli M, Dweck MR, Aikawa E. Creager MD, et al. Among authors: schlotter f. Circ Cardiovasc Imaging. 2019 Jan;12(1):e007835. doi: 10.1161/CIRCIMAGING.118.007835. Circ Cardiovasc Imaging. 2019. PMID: 30642216 Free PMC article.
Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis.
Rogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E. Rogers MA, et al. Among authors: schlotter f. Sci Adv. 2020 Sep 16;6(38):eabb1244. doi: 10.1126/sciadv.abb1244. Print 2020 Sep. Sci Adv. 2020. PMID: 32938681 Free PMC article.
ApoC-III is a novel inducer of calcification in human aortic valves.
Schlotter F, de Freitas RCC, Rogers MA, Blaser MC, Wu PJ, Higashi H, Halu A, Iqbal F, Andraski AB, Rodia CN, Kuraoka S, Wen JR, Creager M, Pham T, Hutcheson JD, Body SC, Kohan AB, Sacks FM, Aikawa M, Singh SA, Aikawa E. Schlotter F, et al. J Biol Chem. 2021 Jan-Jun;296:100193. doi: 10.1074/jbc.RA120.015700. Epub 2021 Jan 6. J Biol Chem. 2021. PMID: 33334888 Free PMC article.
Elastogenesis Correlates With Pigment Production in Murine Aortic Valve Leaflets.
Hutcheson JD, Schlotter F, Creager MD, Li X, Pham T, Vyas P, Higashi H, Body SC, Aikawa M, Singh SA, Kos L, Aikawa E. Hutcheson JD, et al. Among authors: schlotter f. Front Cardiovasc Med. 2021 Jun 22;8:678401. doi: 10.3389/fcvm.2021.678401. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34239903 Free PMC article.
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity.
Iqbal F, Schlotter F, Becker-Greene D, Lupieri A, Goettsch C, Hutcheson JD, Rogers MA, Itoh S, Halu A, Lee LH, Blaser MC, Mlynarchik AK, Hagita S, Kuraoka S, Chen HY, Engert JC, Passos LSA, Jha PK, Osborn EA, Jaffer FA, Body SC, Robson SC, Thanassoulis G, Aikawa M, Singh SA, Sonawane AR, Aikawa E. Iqbal F, et al. Among authors: schlotter f. Eur Heart J. 2023 Mar 7;44(10):885-898. doi: 10.1093/eurheartj/ehac818. Eur Heart J. 2023. PMID: 36660854 Free PMC article.
Dynamin-related protein 1 inhibition reduces hepatic PCSK9 secretion.
Rogers MA, Hutcheson JD, Okui T, Goettsch C, Singh SA, Halu A, Schlotter F, Higashi H, Wang L, Whelan MC, Mlynarchik AK, Daugherty A, Nomura M, Aikawa M, Aikawa E. Rogers MA, et al. Among authors: schlotter f. Cardiovasc Res. 2021 Sep 28;117(11):2340-2353. doi: 10.1093/cvr/cvab034. Cardiovasc Res. 2021. PMID: 33523181 Free PMC article.
Interferon-γ Released by Activated CD8+ T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves.
Nagy E, Lei Y, Martínez-Martínez E, Body SC, Schlotter F, Creager M, Assmann A, Khabbaz K, Libby P, Hansson GK, Aikawa E. Nagy E, et al. Among authors: schlotter f. Am J Pathol. 2017 Jun;187(6):1413-1425. doi: 10.1016/j.ajpath.2017.02.012. Epub 2017 Apr 19. Am J Pathol. 2017. PMID: 28431214 Free PMC article.
56 results