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Page 1
IL-6 selectively suppresses cDC1 specification via C/EBPβ.
Kim S, Chen J, Jo S, Ou F, Ferris ST, Liu TT, Ohara RA, Anderson DA, Wu R, Chen MY, Gillanders WE, Gillanders WE, Murphy TL, Murphy KM. Kim S, et al. Among authors: gillanders we. J Exp Med. 2023 Oct 2;220(10):e20221757. doi: 10.1084/jem.20221757. Epub 2023 Jul 11. J Exp Med. 2023. PMID: 37432392 Free PMC article.
Cross-dressed CD8α+/CD103+ dendritic cells prime CD8+ T cells following vaccination.
Li L, Kim S, Herndon JM, Goedegebuure P, Belt BA, Satpathy AT, Fleming TP, Hansen TH, Murphy KM, Gillanders WE. Li L, et al. Among authors: gillanders we. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12716-21. doi: 10.1073/pnas.1203468109. Epub 2012 Jul 16. Proc Natl Acad Sci U S A. 2012. PMID: 22802630 Free PMC article.
WDFY4 is required for cross-presentation in response to viral and tumor antigens.
Theisen DJ, Davidson JT 4th, Briseño CG, Gargaro M, Lauron EJ, Wang Q, Desai P, Durai V, Bagadia P, Brickner JR, Beatty WL, Virgin HW, Gillanders WE, Mosammaparast N, Diamond MS, Sibley LD, Yokoyama W, Schreiber RD, Murphy TL, Murphy KM. Theisen DJ, et al. Among authors: gillanders we. Science. 2018 Nov 9;362(6415):694-699. doi: 10.1126/science.aat5030. Science. 2018. PMID: 30409884 Free PMC article.
cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity.
Ferris ST, Durai V, Wu R, Theisen DJ, Ward JP, Bern MD, Davidson JT 4th, Bagadia P, Liu T, Briseño CG, Li L, Gillanders WE, Wu GF, Yokoyama WM, Murphy TL, Schreiber RD, Murphy KM. Ferris ST, et al. Among authors: gillanders we. Nature. 2020 Aug;584(7822):624-629. doi: 10.1038/s41586-020-2611-3. Epub 2020 Aug 12. Nature. 2020. PMID: 32788723 Free PMC article.
Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology.
Panni UY, Chen MY, Zhang F, Cullinan DR, Li L, James CA, Zhang X, Rogers S, Alarcon A, Baer JM, Zhang D, Gao F, Miller CA, Gong Q, Lim KH, DeNardo DG, Goedegebuure SP, Gillanders WE, Hawkins WG. Panni UY, et al. Among authors: gillanders we. Cancer Immunol Immunother. 2023 Aug;72(8):2813-2827. doi: 10.1007/s00262-023-03463-x. Epub 2023 May 13. Cancer Immunol Immunother. 2023. PMID: 37179276 Free PMC article.
Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients.
Zhang X, Goedegebuure SP, Chen MY, Mishra R, Zhang F, Yu YY, Singhal K, Li L, Gao F, Myers NB, Vickery T, Hundal J, McLellan MD, Sturmoski MA, Kim SW, Chen I, Davidson JT 4th, Sankpal NV, Myles S, Suresh R, Ma CX, Foluso A, Wang-Gillam A, Davies S, Hagemann IS, Mardis ER, Griffith O, Griffith M, Miller CA, Hansen TH, Fleming TP, Schreiber RD, Gillanders WE. Zhang X, et al. Among authors: gillanders we. Genome Med. 2024 Nov 14;16(1):131. doi: 10.1186/s13073-024-01388-3. Genome Med. 2024. PMID: 39538331 Free PMC article. Clinical Trial.
Development of an adenovirus vector vaccine platform for targeting dendritic cells.
Sharma PK, Dmitriev IP, Kashentseva EA, Raes G, Li L, Kim SW, Lu ZH, Arbeit JM, Fleming TP, Kaliberov SA, Goedegebuure SP, Curiel DT, Gillanders WE. Sharma PK, et al. Among authors: gillanders we. Cancer Gene Ther. 2018 Feb;25(1-2):27-38. doi: 10.1038/s41417-017-0002-1. Epub 2017 Dec 15. Cancer Gene Ther. 2018. PMID: 29242639 Free PMC article.
166 results