Chu W - Search Results

1

Peptide ligands for the affinity purification of adeno-associated viruses from HEK 293 cell lysates.

Chu W, Shastry S, Barbieri E, Prodromou R, Greback-Clarke P, Smith W, Moore B, Kilgore R, Cummings C, Pancorbo J, Gilleskie G, Daniele MA, Menegatti S. Chu W, et al. Biotechnol Bioeng. 2023 Aug;120(8):2283-2300. doi: 10.1002/bit.28495. Epub 2023 Jul 12. Biotechnol Bioeng. 2023. PMID: 37435968 Free PMC article.

2

Novel peptide ligands for antibody purification provide superior clearance of host cell protein impurities.

Reese HR, Xiao X, Shanahan CC, Chu W, Van Den Driessche GA, Fourches D, Carbonell RG, Hall CK, Menegatti S. Reese HR, et al. Among authors: chu w. J Chromatogr A. 2020 Aug 16;1625:461237. doi: 10.1016/j.chroma.2020.461237. Epub 2020 May 23. J Chromatogr A. 2020. PMID: 32709313

3

Peptides and pseudopeptide ligands: a powerful toolbox for the affinity purification of current and next-generation biotherapeutics.

Chu W, Prodromou R, Day KN, Schneible JD, Bacon KB, Bowen JD, Kilgore RE, Catella CM, Moore BD, Mabe MD, Alashoor K, Xu Y, Xiao Y, Menegatti S. Chu W, et al. J Chromatogr A. 2021 Jan 4;1635:461632. doi: 10.1016/j.chroma.2020.461632. Epub 2020 Oct 22. J Chromatogr A. 2021. PMID: 33333349

4

De novo discovery of peptide-based affinity ligands for the fab fragment of human immunoglobulin G.

Xiao X, Kilgore R, Sarma S, Chu W, Menegatti S, Hall CK. Xiao X, et al. Among authors: chu w. J Chromatogr A. 2022 Apr 26;1669:462941. doi: 10.1016/j.chroma.2022.462941. Epub 2022 Mar 6. J Chromatogr A. 2022. PMID: 35303576

5

Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via "flow-through affinity chromatography" using peptide-based adsorbents.

Sripada SA, Chu W, Williams TI, Teten MA, Mosley BJ, Carbonell RG, Lenhoff AM, Cramer SM, Bill J, Yigzaw Y, Roush DJ, Menegatti S. Sripada SA, et al. Among authors: chu w. Biotechnol Bioeng. 2022 Jul;119(7):1873-1889. doi: 10.1002/bit.28096. Epub 2022 Apr 22. Biotechnol Bioeng. 2022. PMID: 35377460

6

Development of peptide ligands for the purification of α-1 antitrypsin from cell culture fluids.

Chu W, Prodromou R, Moore B, Elhanafi D, Kilgore R, Shastry S, Menegatti S. Chu W, et al. J Chromatogr A. 2022 Aug 30;1679:463363. doi: 10.1016/j.chroma.2022.463363. Epub 2022 Jul 22. J Chromatogr A. 2022. PMID: 35964464

7

Development of peptide affinity ligands for the purification of polyclonal and monoclonal Fabs from recombinant fluids.

Kilgore R, Chu W, Bhandari D, Fischler D, Carbonell RG, Crapanzano M, Menegatti S. Kilgore R, et al. Among authors: chu w. J Chromatogr A. 2023 Jan 4;1687:463701. doi: 10.1016/j.chroma.2022.463701. Epub 2022 Dec 5. J Chromatogr A. 2023. PMID: 36502645

8

Molecular engineering of cyclic azobenzene-peptide hybrid ligands for the purification of human blood Factor VIII via photo-affinity chromatography.

Prodromou R, Moore B, Chu W, Deal H, Miguel AS, Brown AC, Daniele MA, Pozdin V, Menegatti S. Prodromou R, et al. Among authors: chu w. Adv Funct Mater. 2023 Apr 4;33(14):2213881. doi: 10.1002/adfm.202213881. Epub 2023 Jan 25. Adv Funct Mater. 2023. PMID: 37576949 Free PMC article.

9

The downstream bioprocess toolbox for therapeutic viral vectors.

Kilgore R, Minzoni A, Shastry S, Smith W, Barbieri E, Wu Y, LeBarre JP, Chu W, O'Brien J, Menegatti S. Kilgore R, et al. Among authors: chu w. J Chromatogr A. 2023 Oct 25;1709:464337. doi: 10.1016/j.chroma.2023.464337. Epub 2023 Sep 9. J Chromatogr A. 2023. PMID: 37722177

10

Rational design and experimental evaluation of peptide ligands for the purification of adeno-associated viruses via affinity chromatography.

Shastry S, Chu W, Barbieri E, Greback-Clarke P, Smith WK, Cummings C, Minzoni A, Pancorbo J, Gilleskie G, Ritola K, Daniele MA, Johnson TF, Menegatti S. Shastry S, et al. Among authors: chu w. Biotechnol J. 2024 Jan;19(1):e2300230. doi: 10.1002/biot.202300230. Epub 2023 Sep 28. Biotechnol J. 2024. PMID: 37728197

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