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Discovery and Evaluation of 3-Quinoxalin Urea Derivatives as Potent, Selective, and Orally Available ATM Inhibitors Combined with Chemotherapy for the Treatment of Cancer via Goal-Oriented Molecule Generation and Virtual Screening.
Deng D, Yang Y, Zou Y, Liu K, Zhang C, Tang M, Yang T, Chen Y, Yuan X, Guo Y, Zhang S, Si W, Peng B, Xu Q, He W, Xu D, Xiang M, Chen L. Deng D, et al. Among authors: liu k. J Med Chem. 2023 Jul 27;66(14):9495-9518. doi: 10.1021/acs.jmedchem.3c00082. Epub 2023 Jul 12. J Med Chem. 2023. PMID: 37438997
Correction to "Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms".
Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: liu k. J Med Chem. 2020 Feb 13;63(3):1441-1442. doi: 10.1021/acs.jmedchem.0c00025. Epub 2020 Jan 27. J Med Chem. 2020. PMID: 31985218 No abstract available.
Synthesis and evaluation of new compounds bearing 3-(4-aminopiperidin-1-yl)methyl magnolol scaffold as anticancer agents for the treatment of non-small cell lung cancer via targeting autophagy.
Zhao M, Zheng YH, Zhao QY, Zheng W, Yang JH, Pei HY, Liu L, Liu KJ, Xue LL, Deng DX, Wang L, Ma X, Fu SH, Peng AH, Tang MH, Luo YZ, Ye HY, Chen LJ. Zhao M, et al. Eur J Med Chem. 2021 Jan 1;209:112922. doi: 10.1016/j.ejmech.2020.112922. Epub 2020 Oct 10. Eur J Med Chem. 2021. PMID: 33069436
Correction to "N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms".
Yang T, Hu M, Chen Y, Xiang M, Tang M, Qi W, Shi M, He J, Yuan X, Zhang C, Liu K, Li J, Yang Z, Chen L. Yang T, et al. Among authors: liu k. J Med Chem. 2021 Feb 25;64(4):2310. doi: 10.1021/acs.jmedchem.1c00198. Epub 2021 Feb 16. J Med Chem. 2021. PMID: 33591746 No abstract available.
Discovery, Optimization, and Evaluation of Quinazolinone Derivatives with Novel Linkers as Orally Efficacious Phosphoinositide-3-Kinase Delta Inhibitors for Treatment of Inflammatory Diseases.
Liu K, Li D, Zheng W, Shi M, Chen Y, Tang M, Yang T, Zhao M, Deng D, Zhang C, Liu J, Yuan X, Yang Z, Chen L. Liu K, et al. Among authors: liu j. J Med Chem. 2021 Jul 8;64(13):8951-8970. doi: 10.1021/acs.jmedchem.1c00004. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138567
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