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Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance.
Rodriguez BL, Chen L, Li Y, Miao S, Peng DH, Fradette JJ, Diao L, Konen JM, Alvarez FRR, Solis LM, Yi X, Padhye A, Gibson LA, Ochieng JK, Zhou X, Wang J, Gibbons DL. Rodriguez BL, et al. Among authors: konen jm. Front Immunol. 2023 Jun 28;14:1161869. doi: 10.3389/fimmu.2023.1161869. eCollection 2023. Front Immunol. 2023. PMID: 37449205 Free PMC article.
Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy.
Soundararajan R, Fradette JJ, Konen JM, Moulder S, Zhang X, Gibbons DL, Varadarajan N, Wistuba II, Tripathy D, Bernatchez C, Byers LA, Chang JT, Contreras A, Lim B, Parra ER, Roarty EB, Wang J, Yang F, Barton M, Rosen JM, Mani SA. Soundararajan R, et al. Among authors: konen jm. Cancers (Basel). 2019 May 24;11(5):714. doi: 10.3390/cancers11050714. Cancers (Basel). 2019. PMID: 31137625 Free PMC article. Review.
Dual Inhibition of MEK and AXL Targets Tumor Cell Heterogeneity and Prevents Resistant Outgrowth Mediated by the Epithelial-to-Mesenchymal Transition in NSCLC.
Konen JM, Rodriguez BL, Padhye A, Ochieng JK, Gibson L, Diao L, Fowlkes NW, Fradette JJ, Peng DH, Cardnell RJ, Kovacs JJ, Wang J, Byers LA, Gibbons DL. Konen JM, et al. Cancer Res. 2021 Mar 1;81(5):1398-1412. doi: 10.1158/0008-5472.CAN-20-1895. Epub 2021 Jan 5. Cancer Res. 2021. PMID: 33402388 Free PMC article.
23 results