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Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling.
Jeon HM, Kim JY, Cho HJ, Lee WJ, Nguyen D, Kim SS, Oh YT, Kim HJ, Jung CW, Pinero G, Joshi T, Hambardzumyan D, Sakaguchi T, Hubert CG, McIntyre TM, Fine HA, Gladson CL, Wang B, Purow BW, Park JB, Park MJ, Nam DH, Lee J. Jeon HM, et al. Among authors: hambardzumyan d. Cancer Cell. 2023 Aug 14;41(8):1480-1497.e9. doi: 10.1016/j.ccell.2023.06.007. Epub 2023 Jul 13. Cancer Cell. 2023. PMID: 37451272 Free PMC article.
Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression.
Sattiraju A, Kang S, Giotti B, Chen Z, Marallano VJ, Brusco C, Ramakrishnan A, Shen L, Tsankov AM, Hambardzumyan D, Friedel RH, Zou H. Sattiraju A, et al. Among authors: hambardzumyan d. Immunity. 2023 Aug 8;56(8):1825-1843.e6. doi: 10.1016/j.immuni.2023.06.017. Epub 2023 Jul 13. Immunity. 2023. PMID: 37451265 Free PMC article.
Author Correction: YB1 modulates the DNA damage response in medulloblastoma.
McSwain LF, Pillsbury CE, Haji-Seyed-Javadi R, Rath SK, Chen V, Huang T, Shahab SW, Kunhiraman H, Ross J, Price GA, Dey A, Hambardzumyan D, MacDonald T, Yu DS, Porter CC, Kenney AM. McSwain LF, et al. Among authors: hambardzumyan d. Sci Rep. 2023 Jun 15;13(1):9717. doi: 10.1038/s41598-023-36594-3. Sci Rep. 2023. PMID: 37322047 Free PMC article. No abstract available.
Genetic and epigenetic instability as an underlying driver of progression and aggressive behavior in IDH-mutant astrocytoma.
Richardson TE, Walker JM, Hambardzumyan D, Brem S, Hatanpaa KJ, Viapiano MS, Pai B, Umphlett M, Becher OJ, Snuderl M, McBrayer SK, Abdullah KG, Tsankova NM. Richardson TE, et al. Among authors: hambardzumyan d. Acta Neuropathol. 2024 Jul 16;148(1):5. doi: 10.1007/s00401-024-02761-7. Acta Neuropathol. 2024. PMID: 39012509 Free PMC article. Review.
Dual MAPK Inhibition Triggers Pro-inflammatory Signals and Sensitizes BRAF V600E Glioma to T Cell-Mediated Checkpoint Therapy.
Xing YL, Grossauer S, Park JW, Nasajpour E, Bui B, Morales D, Panovska D, Nirschl JJ, Feng ZP, Wei R, Koeck K, Thomason W, Xiu J, Harter PN, Filipski K, Mahaney K, Ji X, Mulcahy Levy JM, Grant GA, Prolo LM, Walsh KM, Lim M, Hambardzumyan D, Petritsch CK. Xing YL, et al. Among authors: hambardzumyan d. bioRxiv [Preprint]. 2024 Oct 7:2023.02.03.526065. doi: 10.1101/2023.02.03.526065. bioRxiv. 2024. PMID: 39416185 Free PMC article. Preprint.
Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations.
Ross JL, Puigdelloses-Vallcorba M, Piñero G, Soni N, Thomason W, DeSisto J, Angione A, Tsankova NM, Castro MG, Schniederjan M, Wadhwani NR, Raju GP, Morgenstern P, Becher OJ, Green AL, Tsankov AM, Hambardzumyan D. Ross JL, et al. Among authors: hambardzumyan d. Immunity. 2024 Nov 12;57(11):2669-2687.e6. doi: 10.1016/j.immuni.2024.09.007. Epub 2024 Oct 11. Immunity. 2024. PMID: 39395421
Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence.
Zarco N, Dovas A, de Araujo Farias V, Nagaiah NK, Haddock A, Sims PA, Hambardzumyan D, Meyer CT, Canoll P, Rosenfeld SS, Kenchappa RS. Zarco N, et al. Among authors: hambardzumyan d. bioRxiv [Preprint]. 2024 Jun 9:2024.06.09.598115. doi: 10.1101/2024.06.09.598115. bioRxiv. 2024. Update in: iScience. 2024 Nov 05;27(12):111311. doi: 10.1016/j.isci.2024.111311 PMID: 38895402 Free PMC article. Updated. Preprint.
99 results